{"id":22172,"date":"2023-07-10T11:35:44","date_gmt":"2023-07-10T15:35:44","guid":{"rendered":"https:\/\/www.mesotheliomahope.com\/?page_id=22172"},"modified":"2025-12-10T12:07:26","modified_gmt":"2025-12-10T17:07:26","slug":"targeted-therapies","status":"publish","type":"page","link":"https:\/\/www.mesotheliomahope.com\/treatment\/targeted-therapies\/","title":{"rendered":"Mesothelioma Targeted Therapy"},"content":{"rendered":"<h2>What Is Targeted Treatment for Mesothelioma?<\/h2>\n<p>Targeted treatment for mesothelioma is a type of therapy that focuses on attacking specific changes in cancer cells, rather than affecting the whole body as chemotherapy does. These treatments are designed to block the signals cancer cells use to grow and spread. By zeroing in on the cancer itself, targeted therapy may cause fewer side effects than traditional chemotherapy.<\/p>\n<p>These therapies have shown promise in managing mesothelioma and have been a focus of ongoing research and <a href=\"\/treatment\/clinical-trials\/\">clinical trials<\/a>.<\/p>\n<p>However, it&#8217;s important to note that not all mesothelioma cases can be treated with targeted therapy. You may have to undergo specific genetic or biomarker testing to find out if you\u2019re eligible.<\/p>\n<p>The best way to determine whether you\u2019re a good candidate for targeted therapy is to speak with a specialist. Use our <strong>Free Doctor Match<\/strong> to connect with a mesothelioma specialist near you.<\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>How Does Targeted Therapy Treat Mesothelioma?<\/h2>\n<p>Targeted therapy treats <a href=\"\/mesothelioma\/\">malignant mesothelioma<\/a> by isolating cancer cells and slowing their growth. It accomplishes this in three main ways.<\/p>\n<h3>1. Targeting Proteins<\/h3>\n<p>Healthy cells only divide when they receive signals to do so. Targeted therapies can block these proteins from signaling cell division, slowing the growth and spread of mesothelioma cancer cells.<\/p>\n<p>In contrast, cancer cells have modified proteins on their surface that cause them to divide even if signals are not present. Targeted therapies can stop these proteins from telling cells to divide, causing mesothelioma cancer cells to grow and spread slower.<\/p>\n<p>For example, ipilimumab (Yervoy\u00ae) targets the CTLA-4 protein to encourage the growth of T cells, which are immune cells that attack cancerous cells. Similarly, <a href=\"\/treatment\/immunotherapy\/opdivo-yervoy\/\">nivolumab (Opdivo\u00ae)<\/a> targets the PD-L1 protein to prevent cancer cells from hiding from T cells.<\/p>\n<h3>2. Enhancing the Immune System<\/h3>\n<p>Mesothelioma treatment with targeted therapy can make it easier for your immune system to locate and destroy cancer cells. Targeted treatments can also strengthen your immune system to kill cancer cells more effectively.<\/p>\n<p>These targeted therapies fall under a class of treatments known as immunotherapy. <a href=\"\/treatment\/immunotherapy\/\">Immunotherapy<\/a> is\u00a0a type of biological therapy that uses substances made from living organisms to kill cancer cells.<\/p>\n<p><strong>Immunotherapy drugs fall into two categories:<\/strong><\/p>\n<ul>\n<li><strong>Anti-mesothelin drugs<\/strong> boost the immune response to mesothelin, an antigen that can be found in most malignant pleural mesothelioma cells. An antigen is any substance that can trigger an immune response against that substance.<\/li>\n<li><a href=\"\/treatment\/immunotherapy\/checkpoint-inhibitors\/\"><strong>Checkpoint inhibitors<\/strong><\/a> block immune checkpoints, which are regulators of the immune system that can diminish the body\u2019s ability to attack cancer cells. Examples of checkpoint inhibitors include <a href=\"\/treatment\/immunotherapy\/keytruda\/\">pembrolizumab (Keytruda\u00ae)<\/a>, Opdivo\u00ae, and atezolizumab (Tecentriq\u00ae).<\/li>\n<\/ul>\n<p>Download our <strong>Free Immunotherapy Guide<\/strong> to learn more about this type of targeted mesothelioma treatment.<\/p>\n<div id=\"23756\" class=\"one-off-23756 widget widget_oscar-vque one-off\" data-vqueid=\"23756\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-23756{margin:60px auto}.one-off-23756 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:linear-gradient(90deg,#B1E5EA 0,#0FAEBF 100%);padding:20px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:350px;margin:0 auto}.one-off-23756 a::before{background:#EDF8F9;border-radius:0 0 50% 50%;content:'';position:absolute;top:0;height:87%;width:140%;left:-70px;z-index:0}.one-off-23756 .vque-content,.one-off-23756 .image-wrap{z-index:1;position:relative}.one-off-23756 .image-wrap{max-width:163px;display:block;margin:15px auto -21px}.one-off-23756 .heading{font-size:24px;line-height:28px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-23756 ul{max-width:160px;list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:27px}.one-off-23756 ul li{margin:0;position:relative;padding-left:28px}.one-off-23756 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:14px;height:14px;display:block;position:absolute;left:0;top:7px;border-radius:50%;color:#fff;font-size:7px;text-align:center;line-height:14px}.one-off-23756 p{text-align:center}.one-off-23756 .button{padding:12px 16px}@media screen and (min-width:768px){.one-off-23756 a{max-width:620px;padding:25px 50px 29px;border-radius:0 0 4px 4px}.one-off-23756 a::before{border-radius:0 0 100% 0;height:83%;width:70%;right:-70px;left:unset}.one-off-23756 a::after{background:#EDF8F9;border-radius:0;content:'';position:absolute;top:0;height:82%;width:50%;left:0;z-index:0}.one-off-23756 .heading{text-align:left;margin:5px 0 25px}.one-off-23756 ul{margin:-10px 0 22px}.one-off-23756 .image-wrap{max-width:unset;position:absolute;right:0;bottom:0;margin:0 0 -2px}.one-off-23756 p{text-align:left}}<\/style><a href=\"\/immunotherapy-guide\/\" title=\"Get Your Free Immunotherapy Guide\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Your Free Immunotherapy Guide Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Your Free Immunotherapy Guide<\/strong>\r\n        <ul>\r\n            <li>When it\u2019s used<\/li>\r\n            <li>Types of drugs<\/li>\r\n            <li>Side effects<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Your Free Guide\">Get Your Free Guide<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/03\/download-immunotherapy-guide.png\" alt=\"Free Immunotherapy Guide\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h3>3. Working With Other Therapies to Improve Survival<\/h3>\n<p>Many targeted therapies are combined with other treatments to improve patient outcomes.<\/p>\n<p>For example, some treatment plans combine monoclonal antibodies (a type of targeted therapy that boosts the body\u2019s immune response) with cell-killing substances such as <a href=\"\/treatment\/chemotherapy\/drugs\/\">chemotherapy drugs<\/a>, radiation, and toxins.<\/p>\n<p>When these monoclonal antibodies stick to targets on cancer cells\u2019 surfaces, the cells will absorb the cell-killing substances, resulting in apoptosis (cell death).<\/p>\n<h2>Can Targeted Therapy Cure Mesothelioma?<\/h2>\n<p><strong>There is currently no cure for mesothelioma.<\/strong> However, <a href=\"\/treatment\/emerging-treatments\/\">new drugs and emerging treatments<\/a> such as mesothelioma targeted therapy may be able to extend your life expectancy and quality of life.<\/p>\n<p>For example, a 2022 study published in <em>The Lancet Oncology<\/em> journal tested if a targeted therapy called tazemetostat (Tazverik\u00ae) could prevent pleural mesothelioma from spreading. At 12 weeks in, more than 50% of patients treated saw their cancer temporarily stabilize. Over 30% continued to have stable disease after 24 weeks, which meant their cancer neither improved nor worsened.<\/p>\n<div class=\"blockquote-w-image \"><img decoding=\"async\" src=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2024\/05\/Dr_Marjorie_Zauderer.jpeg\" alt=\"\" \/><blockquote><p>&#8220;This is the first targeted therapy we\u2019ve seen to have a real effect on <strong>slowing or stopping pleural mesothelioma.<\/strong>&#8220;<\/p>\n<footer>&ndash;<cite> Dr. Marjorie Zauderer, mesothelioma specialist &amp; researcher<\/cite><\/footer><\/blockquote><style type=\"text\/css\">.blockquote-w-image{position:relative;margin:40px auto}.blockquote-w-image blockquote{background:none;border-left:none;padding:25px;margin-top:0;padding-bottom:0;font-size:inherit;line-height:inherit}.blockquote-w-image blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote p{margin-bottom:0}.blockquote-w-image img{width:100px;border:none;border-radius:100%;box-shadow:none;position:relative;margin:0 auto}.blockquote-w-image.alternative{margin:60px auto}.blockquote-w-image.alternative blockquote{padding:25px 25px 25px 80px;padding-bottom:25px;background-color:#E4F4F6}.blockquote-w-image.alternative img{position:absolute;left:20px;top:25px;z-index:1;width:50px;border:1px solid #fff;box-shadow:0 0 10px rgba(34,34,34,0.2);border-radius:100%}.blockquote-w-image.with-border{background:none;border-left:4px solid #0FAEBF}.blockquote-w-image.with-border blockquote{background:none;border-radius:0;padding:10px 25px}.blockquote-w-image.with-border blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote:before{display:none}@media screen and (min-width: 769px){.blockquote-w-image img{position:absolute;left:0;top:0}.blockquote-w-image blockquote{padding:0 25px 0 125px;min-height:90px}}@media screen and (min-width: 1024px){.blockquote-w-image.alternative blockquote{padding-left:105px}.blockquote-w-image.alternative blockquote footer cite{font-size:16px}.entry-content .blockquote-w-image.alternative img{width:60px;left:25px}}<\/style><\/div>\n<h2>Types of Targeted Therapy<\/h2>\n<p><strong>There are two main types of mesothelioma targeted therapy:<\/strong><\/p>\n<ol>\n<li><a href=\"\/treatment\/targeted-therapies\/monoclonal-antibodies\/\"><strong>Monoclonal antibodies<\/strong><\/a> are lab-created proteins that enlist your body\u2019s immune system against cancer cells. They can enhance, restore, mimic, or modify the immune system\u2019s attack on cancer and other unwanted cells.<\/li>\n<li><a href=\"\/treatment\/targeted-therapies\/angiogenesis-inhibitors\/small-molecule-drugs\/\"><strong>Small-molecule drugs<\/strong><\/a> can enter cancer cells to destroy them. They can easily breach cells due to their low molecular weight. Once inside cells, they can affect proteins and other molecules, leading to apoptosis. Examples of small-molecule drugs include proteasome inhibitors and tyrosine kinase inhibitors.<\/li>\n<\/ol>\n<div class=\"did-you-know icon-bell\"><style type=\"text\/css\">.did-you-know{background:#F3F2F0;border-radius:10px;margin:40px 0;padding:20px 20px 20px 80px;position:relative}.did-you-know:before{position:absolute;left:20px;top:20px;width:45px;height:45px;background:#0FAEBF;border-radius:50px;color:#fff;text-align:center;line-height:45px;font-size:27px}.did-you-know .heading{font-size:24px;color:#100134;padding:10px 0;display:block;margin:0 0 5px}.did-you-know h2,.did-you-know .h2,.did-you-know h3,.did-you-know .h3{font-size:24px;line-height:1.14}@media screen and (min-width: 1024px){.did-you-know{padding:25px 25px 25px 90px}.did-you-know:before{left:25px;top:25px}.did-you-know .heading{padding:8px 0}.did-you-know h2,.did-you-know .h2,.did-you-know h3,.did-you-know .h3{font-size:24px;line-height:1.14}}<\/style><strong class=\"heading\">Did You Know?<\/strong><p>The <a href=\"\/blog\/niraparib-zejula-mesothelioma-study\/\">NERO trial<\/a> showed that niraparib, a PARP inhibitor, can slow disease progression in mesothelioma patients after initial treatments have failed. Patients taking niraparib saw a 27% reduced risk of cancer progression or death and lived longer before their cancer returned or worsened. This is <strong>the first study to show benefit from a PARP inhibitor in mesothelioma<\/strong>.<\/p>\n<\/div>\n<h2 id=\"eligible\">Eligibility for Mesothelioma Targeted Therapy<\/h2>\n<p>Mesothelioma targeted therapy drugs generally have fewer side effects than other <a href=\"\/treatment\/\">mesothelioma treatments<\/a>, including first-line chemotherapy drugs like carboplatin.<\/p>\n<p>However, they may cause certain side effects, including autoimmune reactions. They may also interfere with common medicines, supplements, and vaccinations.<\/p>\n<div class=\"callout-shortcode\"><style type=\"text\/css\">.callout-shortcode{background:#EDF8F9;border-radius:0 10px 10px 0;padding:20px 20px 20px 24px;margin:40px 0;max-width:860px;position:relative}.callout-shortcode:before{content:\" \";position:absolute;top:0;bottom:0;width:4px;height:100%;left:0;background:linear-gradient(180deg, #0FAEBF 0%, #EDF8F9 100%)}.callout-shortcode .callout-shortcode-heading{color:#100134;font-size:22px;display:block;margin:0 0 15px}.callout-shortcode:first-child{margin-top:0}.callout-shortcode:last-child{margin-bottom:0}.callout-shortcode .img-wrap{margin-bottom:20px}.callout-shortcode.hope>strong{padding-top:17px;padding-bottom:15px;padding-left:74px}.callout-shortcode.hope .img-wrap{left:22px;position:absolute;top:20px;width:59px}.callout-shortcode.hope .img-wrap:before{background:#fff url(\/wp-content\/uploads\/2024\/02\/mh-icon-65.png);background-position:center;background-repeat:no-repeat;background-size:70%;border-radius:30px;bottom:-10px;content:\"\";display:block;height:30px;position:absolute;right:-10px;width:30px}@media screen and (min-width: 768px){.callout-shortcode{padding:25px 25px 25px 34px}.callout-shortcode .callout-shortcode-heading{font-size:24px}.callout-shortcode .img-wrap{margin-bottom:0}.callout-shortcode.has-img{min-height:170px;padding-left:175px}.callout-shortcode.has-img .img-wrap{position:absolute;left:29px;top:25px;width:119px}.callout-shortcode.hope.has-img{padding-left:170px}.callout-shortcode.hope>strong{padding:0}.callout-shortcode.hope .img-wrap{width:109px}.callout-shortcode.hope .img-wrap:before{background-size:66%;bottom:-15px;height:42px;width:42px}}<\/style><div class=\"content\"><p>We can help determine if you\u2019re eligible for targeted therapy. Call <a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a> today to speak with one of our knowledgeable Patient Advocates.<\/p>\n<\/div><\/div>\n<h2>How Targeted Therapy Affects Mesothelioma Tumors<\/h2>\n<p>Targeted therapy offers a promising approach for treating mesothelioma tumors. It can specifically target molecules or proteins involved in their growth and survival with the goal of slowing cancer progression.<\/p>\n<p>Learn more about how mesothelioma targeted therapy can affect tumor growth below.<\/p>\n<h3>1. Stopping Signals That Cause Tumor Growth<\/h3>\n<p>Mesothelioma tumors need to form new blood vessels in order to grow beyond a certain size. This process is known as angiogenesis. Targeted therapies called <a href=\"\/treatment\/targeted-therapies\/angiogenesis-inhibitors\/\">angiogenesis inhibitors<\/a> can interfere with vascular endothelial growth factor (VEGF) receptors to prevent new blood vessels from forming and tumors from getting bigger.<\/p>\n<p>Without new blood vessels, tumors stay small. Angiogenic inhibitors can also cause blood vessels to die, causing tumors to shrink.<\/p>\n<p><a href=\"\/treatment\/immunotherapy\/bevacizumab\/\">Bevacizumab (Avastin\u00ae)<\/a> is a specific type of angiogenesis inhibitor. Doctors and cancer care teams often prescribe bevacizumab combined with chemotherapy drugs like pemetrexed and cisplatin as a first-line treatment for unresectable mesothelioma (which can\u2019t be removed with surgery).<\/p>\n<h3>2. Sending Cytotoxic Substances to Mesothelioma Cells<\/h3>\n<p>Mesothelioma treatment with targeted therapy can also slow mesothelioma tumor growth by sending cytotoxic (cell-killing) substances to cells. Examples of these substances include chemotherapy drugs, toxins, and radiation.<\/p>\n<h3>3. Causing Mesothelioma Tumor Cell Death<\/h3>\n<p>Cancer cells have ways to avoid the dying process, leading to disease progression. Targeted therapies can prevent this by causing mesothelioma cancer cells to go through apoptosis.<\/p>\n<p>Oncologists may use additional treatments after or before targeted therapy to treat tumors, including neoadjuvant chemotherapy (given before surgery), <a href=\"\/treatment\/surgery\/\">mesothelioma surgery<\/a>, and radiation therapy.<\/p>\n<h2>What to Expect During Mesothelioma Targeted Therapy<\/h2>\n<p>Your experience with mesothelioma targeted therapy will depend on the type of therapy you receive. Your overall health and individual response to treatments may also influence how you react to targeted therapy.<\/p>\n<p><strong>Monoclonal antibodies<\/strong> are usually administered intravenously through a needle in a vein. You must undergo monoclonal antibody targeted treatments at a cancer center or hospital.<\/p>\n<p>On the other hand, <strong>small-molecule drugs<\/strong> are administered as capsules or pills you swallow. This means <strong>you can take them on the go or at home<\/strong>.<\/p>\n<p>Treatment frequency depends on your disease progression, your overall health, how your body responds to treatments, and the specific drugs you\u2019re prescribed.<\/p>\n<p>That said, most mesothelioma patients receive targeted treatments daily, weekly, or monthly. However, some targeted therapies are delivered in cycles, just as with chemotherapy.<\/p>\n<h2 id=\"benefits\">Benefits of Mesothelioma Targeted Therapy<\/h2>\n<p>Cancer research has revealed several benefits of targeted therapy for pleural and <a href=\"\/mesothelioma\/peritoneal\/\">peritoneal mesothelioma<\/a>.<\/p>\n<p><strong>These benefits include:<\/strong><\/p>\n<ul>\n<li><strong>Blocking cancer cells from growing:<\/strong> Mesothelioma treatment with targeted therapy can prevent disease progression, as the cancer cells won\u2019t be able to grow or spread.<\/li>\n<li><strong>Having fewer effects on healthy cells:<\/strong> Unlike chemotherapy, targeted therapy damages, weakens, and destroys cancer cells in very specific ways. This results in lower toxicity and reduced damage to healthy cells.<\/li>\n<li><strong>Treating inoperable cancer:<\/strong> Targeted therapy can destroy mesothelioma tumors that are impossible or difficult to remove through surgery.<\/li>\n<\/ul>\n<a href=\"#triggerChat\" class=\"connect-cta alt\" data-ce-category=\"Connect CTA\" data-ce-label=\"Chat Now\"><div><style type=\"text\/css\">a.connect-cta.default{outline:0;display:block;background:#EDF8F9;border-radius:10px;margin:70px auto 40px;max-width:340px;text-align:center;text-decoration:none;padding:22px;color:#383441;line-height:1.5;border:2px solid #0FAEBF}a.connect-cta.default span.img-wrap{display:inline-block;margin:-60px auto 10px;width:74px;height:74px;border:2px solid #0FAEBF;border-radius:70px;position:relative}a.connect-cta.default span.img-wrap:after{background:#26E707;border:1px solid #fff;-webkit-border-radius:12px;-moz-border-radius:12px;border-radius:12px;content:\"\";display:block;height:13px;position:absolute;right:0;top:4px;width:13px;-webkit-animation:animation 2s infinite;-moz-animation:animation 2s infinite;-o-animation:animation 2s infinite;animation:animation 2s infinite}a.connect-cta.default img{display:block}a.connect-cta.default p{margin:0 0 15px 0}a.connect-cta.default p:last-child{margin-bottom:0}a.connect-cta.default .button{border:none;border:2px solid #0FAEBF;box-shadow:none;background:#fff;color:#0FAEBF;padding:13px 16px}a.connect-cta.default .button:hover{background:#0FAEBF;color:#fff;text-decoration:none}a.connect-cta.default:hover{color:#383441}a.connect-cta.alt{background-color:#E4F4F6;border:1px solid #0FAEBF;border-radius:4px;font-size:17px;padding:20px 15px;position:relative;display:block;text-decoration:none;color:inherit;margin:40px auto;max-width:710px;text-align:center}a.connect-cta.alt .img-wrap,a.connect-cta.alt p{display:block;position:relative;vertical-align:middle;margin:0 auto 20px;line-height:1.4}a.connect-cta.alt .img-wrap img,a.connect-cta.alt p img{margin:0 auto}a.connect-cta.alt p.connect-btn{margin-right:0}a.connect-cta.alt .chat-available{position:absolute;left:50%;transform:translateX(-50%);bottom:-13px;background:#fff;font-size:12px;padding:5px 20px 5px 5px;border:1px solid #79D1DA;border-radius:60px;line-height:1;font-weight:700}a.connect-cta.alt .chat-available span{position:relative}a.connect-cta.alt .chat-available span:after{background:#26E707;border:1px solid #fff;-webkit-border-radius:12px;-moz-border-radius:12px;border-radius:12px;content:\"\";display:block;height:8px;position:absolute;right:-13px;top:3px;width:8px;-webkit-animation:animation 2s infinite;-moz-animation:animation 2s infinite;-o-animation:animation 2s infinite;animation:animation 2s infinite}@media screen and (min-width: 768px){a.connect-cta.default{max-width:495px}a.connect-cta.alt{text-align:left;padding-left:40px}a.connect-cta.alt .img-wrap,a.connect-cta.alt p{display:inline-block;margin-right:15px;margin-bottom:0}a.connect-cta.alt p:not(.connect-btn){width:53%}}@-webkit-keyframes animation{0%{background-color:#26E707}50%{background-color:#00B2BF}100%{background-color:#26E707}}@keyframes animation{0%{background-color:#26E707}50%{background-color:#00B2BF}100%{background-color:#26E707}}<\/style><span class=\"img-wrap\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2022\/02\/chat-cta-advocate.png\" alt=\"Advocate Avatar\" class=\"connect-cta-avatar\" \/><\/span><p>Speak with a Patient Advocate to get help finding targeted therapy and other treatments.<\/p>\n<p class=\"connect-btn\"><span class=\"button arrow\">Chat Now<\/span><\/p><div class=\"chat-available\"><span>Available for Chat<\/span><\/div><\/div><\/a>\n<h2>Side Effects of Targeted Therapy for Mesothelioma Patients<\/h2>\n<p>Side effects of targeted therapy vary depending on the patient&#8217;s health and the type of targeted therapy prescribed.<\/p>\n<p><strong>Potential side effects of mesothelioma treatment with targeted therapy include:<\/strong><\/p>\n<\/p>\n<ul class='columns-2'>\n<li>Autoimmune reactions<\/li>\n<li>Blood clotting or bleeding issues<\/li>\n<li>Changes to your hair, skin, and nails<\/li>\n<li>Diarrhea<\/li>\n<li>Dry skin<\/li>\n<li>Elevated liver enzymes<\/li>\n<li>Hair loss or change in hair color<\/li>\n<li>Heart damage (cardiotoxicity)<\/li>\n<li>Interstitial lung disease (pulmonary fibrosis)<\/li>\n<li>Neurologic and heart rhythm changes<\/li>\n<li>Rashes<\/li>\n<li>Tiredness<\/li>\n<\/ul>\n<p>\n<p>You can help reduce the severity of any side effects by eating a healthy diet, getting enough sleep, and exercising regularly. Limiting alcohol and quitting smoking can also reduce potential negative reactions.<\/p>\n<h2>Risks and Dangers of Mesothelioma Targeted Therapy<\/h2>\n<p>Mesothelioma treatment with targeted therapy is generally safe. However, some people may experience serious side effects, including colon perforations (holes that require surgery), severe bleeding, blood clots, kidney problems, heart problems, and slow wound healing.<\/p>\n<p>There is also a risk of developing serious allergic reactions while getting the drugs through an infusion, which can cause low blood pressure and breathing problems. Talk to a <a href=\"\/treatment\/doctors\/\">mesothelioma doctor<\/a> to learn more about the risks and dangers of mesothelioma targeted therapy.<\/p>\n<p><strong>Need help connecting with a mesothelioma specialist for treatment?<\/strong> Use our Free Doctor Match service to get started.<\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>How Does Targeted Therapy Affect Mesothelioma Survival?<\/h2>\n<p>Targeted therapy is an emerging therapy, so there are limited studies about its effect on <a href=\"\/mesothelioma\/prognosis\/survival-rate\/\">mesothelioma survival rates<\/a>.<\/p>\n<p>However, some research suggests that targeted therapy can extend patients\u2019 survival time.<\/p>\n<div class=\"did-you-know icon-bell\"><style type=\"text\/css\">.did-you-know{background:#F3F2F0;border-radius:10px;margin:40px 0;padding:20px 20px 20px 80px;position:relative}.did-you-know:before{position:absolute;left:20px;top:20px;width:45px;height:45px;background:#0FAEBF;border-radius:50px;color:#fff;text-align:center;line-height:45px;font-size:27px}.did-you-know .heading{font-size:24px;color:#100134;padding:10px 0;display:block;margin:0 0 5px}.did-you-know h2,.did-you-know .h2,.did-you-know h3,.did-you-know .h3{font-size:24px;line-height:1.14}@media screen and (min-width: 1024px){.did-you-know{padding:25px 25px 25px 90px}.did-you-know:before{left:25px;top:25px}.did-you-know .heading{padding:8px 0}.did-you-know h2,.did-you-know .h2,.did-you-know h3,.did-you-know .h3{font-size:24px;line-height:1.14}}<\/style><strong class=\"heading\">Did You Know?<\/strong><p>According to the American Cancer Society, targeted therapy has been found to help <a href=\"\/mesothelioma\/pleural\/\">pleural mesothelioma<\/a> patients live longer when given along with the chemotherapy drugs cisplatin (Platinol\u00ae) and pemetrexed (Almita\u00ae) as compared to chemotherapy alone.<\/p>\n<\/div>\n<h2 id=\"cost\">Cost of Targeted Therapy for Mesothelioma<\/h2>\n<p>The cost of targeted therapy depends on your insurance plan, your disease progression, and which drugs are prescribed. However, without insurance, it may cost <strong>tens of thousands of dollars<\/strong> or more to get certain targeted treatments.<\/p>\n<p>If your insurance doesn\u2019t cover targeted therapy, consider hiring a mesothelioma lawyer to determine your options for <a href=\"\/legal\/compensation\/\">mesothelioma compensation<\/a>. If you are eligible, your lawyer can file a mesothelioma lawsuit against the companies responsible for the asbestos exposure that caused your cancer.<\/p>\n<div class=\"callout-shortcode\"><style type=\"text\/css\">.callout-shortcode{background:#EDF8F9;border-radius:0 10px 10px 0;padding:20px 20px 20px 24px;margin:40px 0;max-width:860px;position:relative}.callout-shortcode:before{content:\" \";position:absolute;top:0;bottom:0;width:4px;height:100%;left:0;background:linear-gradient(180deg, #0FAEBF 0%, #EDF8F9 100%)}.callout-shortcode .callout-shortcode-heading{color:#100134;font-size:22px;display:block;margin:0 0 15px}.callout-shortcode:first-child{margin-top:0}.callout-shortcode:last-child{margin-bottom:0}.callout-shortcode .img-wrap{margin-bottom:20px}.callout-shortcode.hope>strong{padding-top:17px;padding-bottom:15px;padding-left:74px}.callout-shortcode.hope .img-wrap{left:22px;position:absolute;top:20px;width:59px}.callout-shortcode.hope .img-wrap:before{background:#fff url(\/wp-content\/uploads\/2024\/02\/mh-icon-65.png);background-position:center;background-repeat:no-repeat;background-size:70%;border-radius:30px;bottom:-10px;content:\"\";display:block;height:30px;position:absolute;right:-10px;width:30px}@media screen and (min-width: 768px){.callout-shortcode{padding:25px 25px 25px 34px}.callout-shortcode .callout-shortcode-heading{font-size:24px}.callout-shortcode .img-wrap{margin-bottom:0}.callout-shortcode.has-img{min-height:170px;padding-left:175px}.callout-shortcode.has-img .img-wrap{position:absolute;left:29px;top:25px;width:119px}.callout-shortcode.hope.has-img{padding-left:170px}.callout-shortcode.hope>strong{padding:0}.callout-shortcode.hope .img-wrap{width:109px}.callout-shortcode.hope .img-wrap:before{background-size:66%;bottom:-15px;height:42px;width:42px}}<\/style><div class=\"content\"><p>Compensation from a successful lawsuit can pay for your medical fees, pain and suffering, and other losses associated with your mesothelioma diagnosis. Call us today at <a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a> to see if you qualify for financial assistance.<\/p>\n<\/div><\/div>\n<h2 id=\"where\">Where Can I Find Targeted Therapy for Mesothelioma?<\/h2>\n<p>Comprehensive <a href=\"\/cancer-centers\/\">cancer centers<\/a> across the nation have access to a range of advanced treatment options, including targeted therapies.<\/p>\n<p><strong>Examples of cancer centers that offer targeted therapy for mesothelioma include:<\/strong><\/p>\n<\/p>\n<ul class='columns-2'>\n<li><a href=\"\/cancer-centers\/brigham-womens-hospital\/\">Brigham and Women\u2019s Hospital<\/a><\/li>\n<li>City of Hope Cancer<\/li>\n<li>Dana-Farber Cancer Institute<\/li>\n<li><a href=\"\/cancer-centers\/mayo-clinic\/\">Mayo Clinic Cancer Center<\/a><\/li>\n<li>Massachusetts General Hospital<\/li>\n<li><a href=\"\/cancer-centers\/md-anderson-cancer-center\/\">MD Anderson Cancer Center<\/a><\/li>\n<li><a href=\"\/cancer-centers\/h-lee-moffitt-cancer-center\/\">H. Lee Moffitt Cancer Center<\/a><\/li>\n<li><a href=\"\/cancer-centers\/ucla-medical-center\/\">UCLA Comprehensive Cancer Center<\/a><\/li>\n<li><a href=\"\/cancer-centers\/ucsf-helen-diller-comprehensive-cancer-center\/\">UCSF Helen Diller Family Comprehensive Cancer Center<\/a><\/li>\n<\/ul>\n<p>\n<h2>Find Mesothelioma Targeted Therapy Programs<\/h2>\n<p>Receiving a mesothelioma diagnosis can be challenging for patients and their loved ones.<\/p>\n<p>If you are interested in receiving mesothelioma targeted therapy, <strong>our team of Patient Advocates is here to help<\/strong>.<\/p>\n<p>Whether it\u2019s getting you in touch with specialists in your area or helping you enroll in clinical trials for emerging therapies, we\u2019re committed to helping patients and their loved ones navigate their mesothelioma diagnosis and treatment journey.<\/p>\n<p>Call us at <strong><a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a><\/strong> or <a href=\"\/about\/contact\/\">fill out our contact form<\/a> to speak with a Patient Advocate.<\/p>\n<div class=\"faq-wrap\"><h2 class=\"faq-wrap-heading\">Mesothelioma Targeted Therapy FAQs<\/h2><div class=\"faq\" data-faq=\"1\"><h3 class=\"faq-heading\">What is the survival rate for targeted therapy?<\/h3><div><p>According to a 2021 study published in the journal <em>Nature Medicine<\/em>, the 1-year survival of mesothelioma patients who remained cancer-free following targeted therapy treatment was 18.2%.<\/p>\n<p>All of the mesothelioma patients in this study were treated with the targeted therapy drug <a href=\"\/treatment\/immunotherapy\/durvalumab\/\">Imfinzi\u00ae (durvalumab)<\/a> and chemotherapy, and were unable to get surgery.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"2\"><h3 class=\"faq-heading\">Is targeted therapy for mesothelioma better than chemotherapy?<\/h3><div><p>Mesothelioma targeted therapy generally has fewer negative effects than <a href=\"\/treatment\/chemotherapy\/\">chemotherapy<\/a>. This is because it has fewer effects on healthy cells. In contrast, chemotherapy affects all fast-growing cells, including healthy, noncancerous cells.<\/p>\n<p>However, targeted therapy comes with potential risks and dangers, including allergic reactions, heart problems, and slow wound healing. Be sure to consult your specialist to see whether targeted therapy is a good fit for you.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"3\"><h3 class=\"faq-heading\">Is mesothelioma targeted therapy covered by health insurance?<\/h3><div><p>Some insurance plans cover mesothelioma targeted therapy and treatments for other types of cancer, but they may not cover the full cost.<\/p>\n<p>If you cannot pay for your targeted therapy, reach out to Mesothelioma Hope for a <a href=\"\/simmons-hanly-conroy\/\">free case review<\/a>. You may be owed compensation that you can use to pay for your cancer treatments.<\/p>\n<\/div><\/div><script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\",\"@type\": \"FAQPage\",\"mainEntity\": [{\"@type\": \"Question\",\"name\": \"What is the survival rate for targeted therapy?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;According to a 2021 study published in the journal &lt;em&gt;Nature Medicine&lt;\/em&gt;, the 1-year survival of mesothelioma patients who remained cancer-free following targeted therapy treatment was 18.2%.&lt;\/p&gt;\n&lt;p&gt;All of the mesothelioma patients in this study were treated with the targeted therapy drug Imfinzi\u00ae (durvalumab) and chemotherapy, and were unable to get surgery.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Is targeted therapy for mesothelioma better than chemotherapy?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Mesothelioma targeted therapy generally has fewer negative effects than chemotherapy. 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You may be owed compensation that you can use to pay for your cancer treatments.&lt;\/p&gt;\n\"}}]}<\/script><style type=\"text\/css\">.faq-wrap{background:#E4F4F6;padding:20px 15px;margin:40px -15px}.faq-wrap:first-child{margin-top:0}.faq-wrap:last-child{margin-bottom:0}.faq-wrap .faq{background:#fff;padding:15px;border-radius:10px;box-shadow:0px 20px 20px rgba(0,0,0,0.03);margin:15px 0 0 0}.faq-wrap .faq:first-child{margin-top:0}.faq-wrap .faq .faq-heading{color:#100134;font-size:21px;margin-bottom:15px}.faq-wrap .faq p{margin-bottom:20px;line-height:1.5}.faq-wrap .faq p:last-child{margin-bottom:0}.faq-wrap .faq .learn-more{color:#248AFF;display:block;padding-right:17px;text-align:right;position:relative;line-height:1}.faq-wrap .faq .learn-more:visited{color:#248AFF}.faq-wrap .faq .learn-more:visited:hover,.faq-wrap .faq .learn-more:hover{color:#34d}.faq-wrap .faq .learn-more:after{font-family:\"mesohope\" !important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e905\";position:absolute;right:0;top:3px}h2.faq-wrap-heading{margin-bottom:25px}@media screen and (min-width: 768px){.faq-wrap{padding:25px 15px}}@media screen and (min-width: 1024px){.faq-wrap{border-radius:10px;margin-left:auto;margin-right:auto;padding:25px}.faq-wrap .faq{padding:25px}.faq-heading{font-size:24px}}<\/style><\/div>\n","protected":false},"excerpt":{"rendered":"<p>What Is Targeted Treatment for Mesothelioma? Targeted treatment for mesothelioma is a type of therapy that focuses on attacking specific changes in cancer cells, rather than affecting the whole body as chemotherapy does. These treatments are designed to block the signals cancer cells use to grow and spread. By zeroing in on the cancer itself,&hellip;<\/p>\n","protected":false},"author":49,"featured_media":0,"parent":39,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-22172","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/22172","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/comments?post=22172"}],"version-history":[{"count":0,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/22172\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/39"}],"wp:attachment":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media?parent=22172"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}