{"id":22851,"date":"2023-11-09T17:33:37","date_gmt":"2023-11-09T22:33:37","guid":{"rendered":"https:\/\/www.mesotheliomahope.com\/?page_id=22851"},"modified":"2025-06-23T21:10:04","modified_gmt":"2025-06-24T01:10:04","slug":"opdivo-yervoy","status":"publish","type":"page","link":"https:\/\/www.mesotheliomahope.com\/treatment\/immunotherapy\/opdivo-yervoy\/","title":{"rendered":"Opdivo and Yervoy for Mesothelioma Immunotherapy"},"content":{"rendered":"<h2>What Is Opdivo?<\/h2>\n<p>Opdivo (generic name nivolumab) is <strong>one of the first <a href=\"\/treatment\/immunotherapy\/\">immunotherapy drugs<\/a> approved for pleural mesothelioma<\/strong>, along with Yervoy (generic name ipilimumab).<\/p>\n<p>In October 2020, the U.S. Food and Drug Administration (FDA) approved the combination of Opdivo and Yervoy for pleural mesothelioma patients who aren\u2019t eligible for surgery. Prior to this, both drugs had already been approved to treat other cancers.<\/p>\n<div class=\"callout-shortcode\"><style type=\"text\/css\">.callout-shortcode{background:#EDF8F9;border-radius:0 10px 10px 0;padding:20px 20px 20px 24px;margin:40px 0;max-width:860px;position:relative}.callout-shortcode:before{content:\" \";position:absolute;top:0;bottom:0;width:4px;height:100%;left:0;background:linear-gradient(180deg, #0FAEBF 0%, #EDF8F9 100%)}.callout-shortcode .callout-shortcode-heading{color:#100134;font-size:22px;display:block;margin:0 0 15px}.callout-shortcode:first-child{margin-top:0}.callout-shortcode:last-child{margin-bottom:0}.callout-shortcode .img-wrap{margin-bottom:20px}.callout-shortcode.hope>strong{padding-top:17px;padding-bottom:15px;padding-left:74px}.callout-shortcode.hope .img-wrap{left:22px;position:absolute;top:20px;width:59px}.callout-shortcode.hope .img-wrap:before{background:#fff url(\/wp-content\/uploads\/2024\/02\/mh-icon-65.png);background-position:center;background-repeat:no-repeat;background-size:70%;border-radius:30px;bottom:-10px;content:\"\";display:block;height:30px;position:absolute;right:-10px;width:30px}@media screen and (min-width: 768px){.callout-shortcode{padding:25px 25px 25px 34px}.callout-shortcode .callout-shortcode-heading{font-size:24px}.callout-shortcode .img-wrap{margin-bottom:0}.callout-shortcode.has-img{min-height:170px;padding-left:175px}.callout-shortcode.has-img .img-wrap{position:absolute;left:29px;top:25px;width:119px}.callout-shortcode.hope.has-img{padding-left:170px}.callout-shortcode.hope>strong{padding:0}.callout-shortcode.hope .img-wrap{width:109px}.callout-shortcode.hope .img-wrap:before{background-size:66%;bottom:-15px;height:42px;width:42px}}<\/style><div class=\"content\"><p>In clinical trials, ipilimumab and nivolumab helped patients diagnosed with <a href=\"\/mesothelioma\/pleural\/\">malignant pleural mesothelioma<\/a> live 4 months longer on average than chemotherapy.<\/p>\n<\/div><\/div>\n<h3>Key Facts on Opdivo for Mesothelioma<\/h3>\n<ul>\n<li><strong>Generic name:<\/strong> Nivolumab<\/li>\n<li><strong>Combined treatments:<\/strong> Yervoy and chemotherapy drugs like cisplatin, carboplatin, and platinum plus<\/li>\n<li><strong>Delivery method:<\/strong> Intravenous (IV) injection<\/li>\n<li><strong>Possible side effects:<\/strong> Fatigue, muscle and bone pain, rash, decreased appetite, dyspnea (shortness of breath), diarrhea, cough, nausea, pruritus (itching at injection site)<\/li>\n<li><strong>Patient eligibility factors<\/strong>: Patients must be in good overall health, have advanced-stage mesothelioma, and have the epithelial or biphasic <a href=\"\/mesothelioma\/cell-types\/\">mesothelioma cell types<\/a> to receive Opdivo.<\/li>\n<li><strong>Impact on survival rate:<\/strong> When used with Yervoy, the 2-year median survival rate is 41% (compared to 27% for chemotherapy alone).<\/li>\n<\/ul>\n<p>Learn more about how Opdivo and Yervoy work in our <strong>Free Immunotherapy Guide.<\/strong><\/p>\n<div id=\"23756\" class=\"one-off-23756 widget widget_oscar-vque one-off\" data-vqueid=\"23756\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-23756{margin:60px auto}.one-off-23756 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:linear-gradient(90deg,#B1E5EA 0,#0FAEBF 100%);padding:20px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:350px;margin:0 auto}.one-off-23756 a::before{background:#EDF8F9;border-radius:0 0 50% 50%;content:'';position:absolute;top:0;height:87%;width:140%;left:-70px;z-index:0}.one-off-23756 .vque-content,.one-off-23756 .image-wrap{z-index:1;position:relative}.one-off-23756 .image-wrap{max-width:163px;display:block;margin:15px auto -21px}.one-off-23756 .heading{font-size:24px;line-height:28px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-23756 ul{max-width:160px;list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:27px}.one-off-23756 ul li{margin:0;position:relative;padding-left:28px}.one-off-23756 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:14px;height:14px;display:block;position:absolute;left:0;top:7px;border-radius:50%;color:#fff;font-size:7px;text-align:center;line-height:14px}.one-off-23756 p{text-align:center}.one-off-23756 .button{padding:12px 16px}@media screen and (min-width:768px){.one-off-23756 a{max-width:620px;padding:25px 50px 29px;border-radius:0 0 4px 4px}.one-off-23756 a::before{border-radius:0 0 100% 0;height:83%;width:70%;right:-70px;left:unset}.one-off-23756 a::after{background:#EDF8F9;border-radius:0;content:'';position:absolute;top:0;height:82%;width:50%;left:0;z-index:0}.one-off-23756 .heading{text-align:left;margin:5px 0 25px}.one-off-23756 ul{margin:-10px 0 22px}.one-off-23756 .image-wrap{max-width:unset;position:absolute;right:0;bottom:0;margin:0 0 -2px}.one-off-23756 p{text-align:left}}<\/style><a href=\"\/immunotherapy-guide\/\" title=\"Get Your Free Immunotherapy Guide\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Your Free Immunotherapy Guide Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Your Free Immunotherapy Guide<\/strong>\r\n        <ul>\r\n            <li>When it\u2019s used<\/li>\r\n            <li>Types of drugs<\/li>\r\n            <li>Side effects<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Your Free Guide\">Get Your Free Guide<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/03\/download-immunotherapy-guide.png\" alt=\"Free Immunotherapy Guide\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>What Are the Benefits of Opdivo for Mesothelioma?<\/h2>\n<p>Opdivo is ideal for pleural mesothelioma patients who don&#8217;t qualify for surgery or have <a href=\"\/mesothelioma\/stages\/\">advanced-stage mesothelioma<\/a> that has spread to other parts of the body.<\/p>\n<p>There are several benefits of taking Opdivo for mesothelioma.<\/p>\n<p><strong>These benefits include:<\/strong><\/p>\n<ul>\n<li><strong>Improved quality of life.<\/strong> Opdivo may help reduce symptoms, such as shortness of breath and chest pain, leading to a higher quality of life.<\/li>\n<li><strong>Longer life expectancy.<\/strong> By enhancing the body&#8217;s immune response, Opdivo has the potential to extend survival time and offer hope to patients and their families.<\/li>\n<li><strong>Potential alternative to other treatments.<\/strong> Opdivo can be considered when other treatments are no longer effective, providing a new avenue to managing this cancer.<\/li>\n<\/ul>\n<h2>How Does Opdivo Work for Mesothelioma?<\/h2>\n<p>Opdivo boosts the body&#8217;s immune system so special cells called T cells are able to attack mesothelioma cells. Learn more about how it works below.<\/p>\n<h3>1. Opdivo Interacts With T Cells<\/h3>\n<p>T cells, a crucial component of the immune system, identify and neutralize foreign threats or abnormal cells in the body, including cancer cells.<\/p>\n<p>In patients diagnosed with <a href=\"\/mesothelioma\/\">mesothelioma<\/a>, cancer cells can hide from T cells and make them inactive. Inactive T cells are unable to attack cancer.<\/p>\n<p>Opdivo works by blocking this signal, allowing T cells to recognize and attack mesothelioma cells.<\/p>\n<h3>2. Opdivo Blocks PD-1<\/h3>\n<p>Opdivo is engineered to act as an immune checkpoint inhibitor and targets the <a href=\"\/treatment\/immunotherapy\/pd1-and-pdl1-inhibitors\/\">PD-1 protein<\/a>.<\/p>\n<p>In simple terms, a PD-1 receptor (Programmed Cell Death Protein 1 receptor) acts like a \u201cbrake\u201d to control and regulate the body\u2019s immune response.<\/p>\n<p>By blocking immune checkpoints like PD-1, Opdivo ensures that the immune system can recognize and attack cancer cells more efficiently, reducing their ability to evade detection.<\/p>\n<h3>3. T Cells Recognize and Attack Mesothelioma Cancer Cells<\/h3>\n<p>By blocking PD-1, Opdivo ensures that T cells can &#8220;see&#8221; mesothelioma cells more clearly.<\/p>\n<p>The activated T cells launch an immune response to attack the pleural mesothelioma tumor cells. This immune response can shrink tumors, slow down cancer growth, and even lead to <a href=\"\/mesothelioma\/prognosis\/remission-recurrence\/\">partial or complete remission<\/a> in some cases.<\/p>\n<p>A <a href=\"\/treatment\/doctors\/\">mesothelioma doctor<\/a> can offer more details on how this process works and answer any questions you have about immunotherapy. <strong>Use our Free Doctor Match to find local specialists today.<\/strong><\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>Opdivo Side Effects<\/h2>\n<p>Opdivo, like many medications, can cause some patients to experience side effects that range from mild to more severe.<\/p>\n<\/p>\n<p><strong>Some common Opdivo side effects include:<\/strong><\/p>\n<ul class='columns-2'>\n<li>Cough<\/li>\n<li>Diarrhea<\/li>\n<li>Dyspnea (shortness of breath)<\/li>\n<li>Nausea<\/li>\n<li>Pain in muscles, bones, and joints<\/li>\n<li>Rashes and itchiness at the injection site (pruritis)<\/li>\n<li>Tiredness<\/li>\n<\/ul>\n<p>\n<p>Opdivo can also cause your T cells to attack the healthy cells in your organs, like your lungs, liver, and thyroid glands. This can harm them and cause issues like <strong>immune-mediated pneumonitis (inflamed lung tissue), colitis (inflamed colon), and hypothyroidism<\/strong>.<\/p>\n<p>Your health care team will educate you about potential Opdivo side effects and develop a plan to manage them.<\/p>\n<h2>Combining Opdivo and Yervoy for Mesothelioma<\/h2>\n<p>Opdivo and Yervoy both fall under the class of medications known as <a href=\"\/treatment\/immunotherapy\/checkpoint-inhibitors\/\">immune checkpoint inhibitors<\/a>.<\/p>\n<p>The synergy between Opdivo and Yervoy enhances the body&#8217;s immune response, offering a potent combination against cancer cells.<\/p>\n<p><strong>Here&#8217;s how they work together:<\/strong><\/p>\n<ul>\n<li><strong>Opdivo starts to activate T cells:<\/strong> Opdivo blocks the PD-1 receptors, activating your immune system\u2019s T cells to defend against the cancer cells.<\/li>\n<li><strong>Yervoy continues this process:<\/strong> Yervoy complements Opdivo by blocking another immune checkpoint protein on T cells called <a href=\"\/treatment\/immunotherapy\/ctla4\/\">CTLA-4<\/a>.<\/li>\n<li><strong>Both drugs offer a combined boost:<\/strong> Opdivo and Yervoy have a combined effect that supercharges your T cells\u2019 ability to seek and destroy mesothelioma cells.<\/li>\n<\/ul>\n<h2>What to Expect During Treatment With Opdivo and Yervoy<\/h2>\n<p>If you or a loved one qualifies for immunotherapy treatment with Opdivo and Yervoy, there are a few things you can generally expect. Read more about the infusion process and required follow-up care below.<\/p>\n<h3>1. Opdivo Infusion Sessions Every 3 Weeks<\/h3>\n<p>Opdivo is administered through IV infusion. Patients typically receive treatment every three weeks. The infusion process usually lasts about 30 minutes.<\/p>\n<p>Your health care team will ensure you are comfortable during the infusion process and address questions or concerns you may have.<\/p>\n<h3>2. Yervoy Infusion Sessions Every 6 Weeks<\/h3>\n<p>If you are receiving both Opdivo and Yervoy, you\u2019ll get a Yervoy infusion along with an Opdivo infusion every 6 weeks. These infusions may also take about an hour (30 minutes for each).<\/p>\n<p>Similar to Opdivo, you will undergo pre-infusion medical assessments and be closely monitored by health care professionals during the session.<\/p>\n<h3>3. Comprehensive Follow-Up Care<\/h3>\n<p>When taking Opdivo for mesothelioma, getting the right follow-up care is important so your health care team can monitor your progress.<\/p>\n<p>The specifics of your follow-up care will vary depending on your <a href=\"\/treatment\/\">mesothelioma treatment plan<\/a> and how you respond to Opdivo.<\/p>\n<p><strong>Your follow-up care may include:<\/strong><\/p>\n<ul>\n<li>Regular check-ups with your health care team to monitor your progress<\/li>\n<li>Imaging tests such as computed tomography (CT) and magnetic resonance imaging (MRI) scans<\/li>\n<li>Adjustments or additions to your treatment plan<\/li>\n<li><a href=\"\/treatment\/diet-and-nutrition\/\">Changes to your diet<\/a> to reduce side effects and help you recover from treatment<\/li>\n<li>Healthy lifestyle habits such as staying physically active and getting enough sleep<\/li>\n<\/ul>\n<p>Your mesothelioma doctor can provide a detailed breakdown of what to expect and address any concerns you may have about Opdivo and Yervoy.<\/p>\n<p>Bring our <strong>Free Questions to Ask Your Doctor checklist<\/strong> to your next appointment to get answers and peace of mind before starting treatment.<\/p>\n<div data-vqueid=\"18575\" class=\"widget widget_oscar-vque outline image-left has-img\"><style type=\"text\/css\" data-style=\"outline\">.widget_oscar-vque.outline{margin:60px auto;max-width:315px}.widget_oscar-vque.outline:first-child{margin-top:0}.widget_oscar-vque.outline:last-child{margin-bottom:0}.widget_oscar-vque.outline>a{border:1px solid #E6E7EC;padding:20px;box-shadow:0 20px 20px rgba(34,34,34,0.03);border-radius:10px;color:#383441;display:block;text-decoration:none}.widget_oscar-vque.outline img{margin:0 auto 20px;max-width:180px}.widget_oscar-vque.outline .vque-content{color:#383441;font-size:16px;text-align:center}.widget_oscar-vque.outline strong.subheading{color:#100134;display:block;line-height:1;font-size:14px;margin-bottom:5px}.widget_oscar-vque.outline strong.heading{color:#100134;font-size:20px;display:block;margin:0 0 20px}.widget_oscar-vque.outline ul{font-size:16px;text-align:left;list-style:none;max-width:265px;margin:15px auto 25px}.widget_oscar-vque.outline ul li{padding-left:28px;margin-bottom:10px}.widget_oscar-vque.outline ul li:last-child{margin-bottom:0}.widget_oscar-vque.outline ul li:before{font-family:\"mesohope\" !important;font-display:swap;speak:none;color:#fff;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e904\";border:none;position:absolute;left:0;top:3px;background:#0FAEBF;width:20px;height:20px;border-radius:20px;line-height:20px;text-align:center;font-size:12px}.widget_oscar-vque.outline strong.button.arrow{width:100%}.widget_oscar-vque.outline.image-left>a{position:relative;border-radius:0 10px 10px 0}.widget_oscar-vque.outline.image-left>a:before{content:\" \";position:absolute;top:0;bottom:0;width:4px;height:100%;left:0;background:linear-gradient(180deg, #0FAEBF 0%, #fff 100%)}@media screen and (min-width: 768px){.widget_oscar-vque.outline{max-width:620px}.widget_oscar-vque.outline img{max-width:100%}.widget_oscar-vque.outline>a{padding:0}.widget_oscar-vque.outline>a>div{display:block;display:flex;flex-wrap:wrap;align-items:flex-end;flex-direction:row-reverse}.widget_oscar-vque.outline>a>div>div{width:41%}.widget_oscar-vque.outline>a .vque-content{width:59%;padding:30px;text-align:left}.widget_oscar-vque.outline strong.subheading{font-size:16px}.widget_oscar-vque.outline strong.heading{font-size:24px;margin:0 0 13px}.widget_oscar-vque.outline ul{max-width:none}.widget_oscar-vque.outline strong.button.arrow{width:auto}.widget_oscar-vque.outline.image-left>a>div{display:block;position:relative;overflow:hidden}.widget_oscar-vque.outline.image-left>a>div>div{float:left}.widget_oscar-vque.outline.image-left>a>div>div:first-child{width:27%;padding:30px}.widget_oscar-vque.outline.image-left>a>div>div.vque-content{width:73%;padding-left:0;color:#383441}}<\/style><a href=\"\/doctor-questions\/\" title=\"Free Download: 14 Questions to Ask\u00a0Your Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Free Download: 14 Questions to Ask\u00a0Your Doctor Ad\" data-desktop-image=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2021\/05\/questions-to-ask-doctor-ipad.png\"><div><div><img loading=\"lazy\" decoding=\"async\" width=\"95\" height=\"144\" src=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2021\/05\/questions-to-ask-doctor-ipad.png\" class=\"attachment-Medium size-Medium wp-post-image\" alt=\"14 Questions to Ask Your Doctor packet\" \/><\/div><div class=\"vque-content\"><strong class=\"heading\">Free Download: 14 Questions to Ask\u00a0Your Doctor<\/strong><ul>\n<li>Preparing for treatment<\/li>\n<li>Finding clinical trials<\/li>\n<li>Getting a second opinion<\/li>\n<\/ul>\n<p><strong class=\"button yellow arrow\" title=\"Get Your Free Download\">Get Your Free Download<\/strong><\/p><\/div><\/div><\/a><\/div>\n<h2>Clinical Research on Opdivo and Yervoy for Mesothelioma<\/h2>\n<p>Opdivo and Yervoy were approved as a first-line (standard) mesothelioma treatment after <a href=\"\/treatment\/clinical-trials\/\">clinical trials<\/a> showed they could help patients live longer.<\/p>\n<p>The <strong>CheckMate 743 trial<\/strong> compared the combination of Opdivo and Yervoy against chemotherapy in a group of patients with pleural mesothelioma.<\/p>\n<div class=\"callout-shortcode\"><style type=\"text\/css\">.callout-shortcode{background:#EDF8F9;border-radius:0 10px 10px 0;padding:20px 20px 20px 24px;margin:40px 0;max-width:860px;position:relative}.callout-shortcode:before{content:\" \";position:absolute;top:0;bottom:0;width:4px;height:100%;left:0;background:linear-gradient(180deg, #0FAEBF 0%, #EDF8F9 100%)}.callout-shortcode .callout-shortcode-heading{color:#100134;font-size:22px;display:block;margin:0 0 15px}.callout-shortcode:first-child{margin-top:0}.callout-shortcode:last-child{margin-bottom:0}.callout-shortcode .img-wrap{margin-bottom:20px}.callout-shortcode.hope>strong{padding-top:17px;padding-bottom:15px;padding-left:74px}.callout-shortcode.hope .img-wrap{left:22px;position:absolute;top:20px;width:59px}.callout-shortcode.hope .img-wrap:before{background:#fff url(\/wp-content\/uploads\/2024\/02\/mh-icon-65.png);background-position:center;background-repeat:no-repeat;background-size:70%;border-radius:30px;bottom:-10px;content:\"\";display:block;height:30px;position:absolute;right:-10px;width:30px}@media screen and (min-width: 768px){.callout-shortcode{padding:25px 25px 25px 34px}.callout-shortcode .callout-shortcode-heading{font-size:24px}.callout-shortcode .img-wrap{margin-bottom:0}.callout-shortcode.has-img{min-height:170px;padding-left:175px}.callout-shortcode.has-img .img-wrap{position:absolute;left:29px;top:25px;width:119px}.callout-shortcode.hope.has-img{padding-left:170px}.callout-shortcode.hope>strong{padding:0}.callout-shortcode.hope .img-wrap{width:109px}.callout-shortcode.hope .img-wrap:before{background-size:66%;bottom:-15px;height:42px;width:42px}}<\/style><div class=\"content\"><p>The trial showed that patients who received Opdivo and Yervoy for mesothelioma had an average survival of 18.1 months, compared to 14.1 months for the patients who received chemotherapy.<\/p>\n<\/div><\/div>\n<p>After 3 years, 23% of the same patients were still alive, and 14% had seen no progression in their cancer.<\/p>\n<p>Opdivo continues to be tested in mesothelioma clinical trials for different stages of mesothelioma and in combination with other treatments like chemotherapy and surgery.<\/p>\n<h2>See if Opdivo and Yervoy Are Right for You<\/h2>\n<p>Opdivo and Yervoy are changing the landscape of mesothelioma treatment and providing newfound hope to patients.<\/p>\n<p>Their proven ability to extend survival, improve quality of life, and promote cancer remission make them a valuable tool in the fight against mesothelioma.<\/p>\n<p>If you or a loved one is battling mesothelioma, our team of nurses and Patient Advocates can help you find out if Opdivo and Yervoy should be part of your treatment plan.<\/p>\n<p>Call us now at <strong><a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a><\/strong> or use our <a href=\"\/get-matched\/\">Free Doctor Match<\/a> to get connected with top mesothelioma specialists in your area.<\/p>\n<div class=\"faq-wrap\"><h2 class=\"faq-wrap-heading\">Opdivo and Yervoy for Mesothelioma Immunotherapy FAQs<\/h2><div class=\"faq\" data-faq=\"1\"><h3 class=\"faq-heading\">Is nivolumab approved for mesothelioma?<\/h3><div><p><strong>Yes,<\/strong> nivolumab for mesothelioma is approved by the U.S. Food and Drug Administration (FDA) in combination with ipilimumab. Nivolumab and ipilimumab are more commonly known as Opdivo and Yervoy, respectively.<\/p>\n<p>It\u2019s important to note that this combination is only approved for patients diagnosed with pleural mesothelioma (cancer of the lung lining) who aren\u2019t able to have surgery.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"2\"><h3 class=\"faq-heading\">What is the success rate of nivolumab for mesothelioma patients?<\/h3><div><p>Results from the CheckMate 743 clinical trial showed that nivolumab combined with ipilimumab (another immune checkpoint inhibitor)<strong> reduced the risk of death from mesothelioma by 26% compared to platinum-based chemotherapy.<\/strong><\/p>\n<p>Its success in improving survival is one of the primary reasons this immunotherapy regimen has been approved to treat mesothelioma patients for whom surgery isn\u2019t an option.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"3\"><h3 class=\"faq-heading\">How much does Opdivo cost?<\/h3><div><p>According to a 2022 <em>Frontiers in Oncology<\/em> report, it can cost more than<strong> $292,000 per year<\/strong> to receive Opdivo and Yervoy for mesothelioma.<\/p>\n<p>The exact cost depends on your treatment plan and whether you have health insurance.<\/p>\n<p>Fortunately, you may be eligible for financial aid to help you pay for Opdivo, Yervoy, and other treatments.<\/p>\n<p>If you qualify, Mesothelioma Hope\u2019s Patient Advocates can <strong>help you pursue compensation<\/strong> from legal claims, asbestos trust funds, and other sources.<\/p>\n<p>Connect with a Patient Advocate now at <strong><a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a><\/strong> to learn more about your options for financial assistance.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"4\"><h3 class=\"faq-heading\">How long can you take Opdivo for mesothelioma?<\/h3><div><p>You can receive Opdivo for mesothelioma for <strong>up to 2 years<\/strong> if you don\u2019t have severe side effects, according to the medication\u2019s manufacturer (Bristol-Myers Squibb).<\/p>\n<p>Your health care team will determine the appropriate treatment duration for your case.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"5\"><h3 class=\"faq-heading\">How long does it take for Opdivo to work?<\/h3><div><p>How long it takes Opdivo to work can vary from person to person.<\/p>\n<p>Some patients may experience benefits in a few weeks to months, while for others it takes a year or more.<\/p>\n<p>Your medical team will closely monitor your progress and adjust your treatment plan as needed.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"6\"><h3 class=\"faq-heading\">How do I know if Opdivo is working?<\/h3><div><p>Your health care team will assess the effectiveness of Opdivo through various means, including imaging studies and regular check-ups.<\/p>\n<p>Opdivo may be working if your cancer tumors shrink or stop growing, or if your cancer symptoms decrease.<\/p>\n<p>If your doctor determines Opdivo for mesothelioma is not effective in your case, they can help you explore other treatment options.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"7\"><h3 class=\"faq-heading\">What are the long-term side effects of Opdivo?<\/h3><div><p>You may experience a number of side effects while being treated with Opdivo.<\/p>\n<p><strong>Long-term Opdivo side effects include:<\/strong><\/p>\n<ul class=\"columns-2\">\n<li>Arthralgia (joint pain) and myalgia (muscle pain)<\/li>\n<li>Colitis (inflammation of the colon)<\/li>\n<li>Diarrhea<\/li>\n<li>Hepatitis (liver inflammation)<\/li>\n<li>Kidney problems<\/li>\n<li>Nervous system issues<\/li>\n<li>Pneumonitis (lung inflammation)<\/li>\n<li>Skin issues (rash or pruritus)<\/li>\n<li>Thyroid disorders (hypothyroidism or hyperthyroidism)<\/li>\n<\/ul>\n<p>You may experience side effects because Opdivo stimulates T cells, which could attack healthy organs and cells while working to kill mesothelioma cells.<\/p>\n<\/div><\/div><script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\",\"@type\": \"FAQPage\",\"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Is nivolumab approved for mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;&lt;strong&gt;Yes,&lt;\/strong&gt; nivolumab for mesothelioma is approved by the U.S. Food and Drug Administration (FDA) in combination with ipilimumab. Nivolumab and ipilimumab are more commonly known as Opdivo and Yervoy, respectively.&lt;\/p&gt;\n&lt;p&gt;It\u2019s important to note that this combination is only approved for patients diagnosed with pleural mesothelioma (cancer of the lung lining) who aren\u2019t able to have surgery.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"What is the success rate of nivolumab for mesothelioma patients?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Results from the CheckMate 743 clinical trial showed that nivolumab combined with ipilimumab (another immune checkpoint inhibitor)&lt;strong&gt; reduced the risk of death from mesothelioma by 26% compared to platinum-based chemotherapy.&lt;\/strong&gt;&lt;\/p&gt;\n&lt;p&gt;Its success in improving survival is one of the primary reasons this immunotherapy regimen has been approved to treat mesothelioma patients for whom surgery isn\u2019t an option.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"How much does Opdivo cost?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;According to a 2022 &lt;em&gt;Frontiers in Oncology&lt;\/em&gt; report, it can cost more than&lt;strong&gt; $292,000 per year&lt;\/strong&gt; to receive Opdivo and Yervoy for mesothelioma.&lt;\/p&gt;\n&lt;p&gt;The exact cost depends on your treatment plan and whether you have health insurance.&lt;\/p&gt;\n&lt;p&gt;Fortunately, you may be eligible for financial aid to help you pay for Opdivo, Yervoy, and other treatments.&lt;\/p&gt;\n&lt;p&gt;If you qualify, Mesothelioma Hope\u2019s Patient Advocates can &lt;strong&gt;help you pursue compensation&lt;\/strong&gt; from legal claims, asbestos trust funds, and other sources.&lt;\/p&gt;\n&lt;p&gt;Connect with a Patient Advocate now at &lt;strong&gt;(866) 608-8933&lt;\/strong&gt; to learn more about your options for financial assistance.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"How long can you take Opdivo for mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;You can receive Opdivo for mesothelioma for &lt;strong&gt;up to 2 years&lt;\/strong&gt; if you don\u2019t have severe side effects, according to the medication\u2019s manufacturer (Bristol-Myers Squibb).&lt;\/p&gt;\n&lt;p&gt;Your health care team will determine the appropriate treatment duration for your case.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"How long does it take for Opdivo to work?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;How long it takes Opdivo to work can vary from person to person.&lt;\/p&gt;\n&lt;p&gt;Some patients may experience benefits in a few weeks to months, while for others it takes a year or more.&lt;\/p&gt;\n&lt;p&gt;Your medical team will closely monitor your progress and adjust your treatment plan as needed.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"How do I know if Opdivo is working?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Your health care team will assess the effectiveness of Opdivo through various means, including imaging studies and regular check-ups.&lt;\/p&gt;\n&lt;p&gt;Opdivo may be working if your cancer tumors shrink or stop growing, or if your cancer symptoms decrease.&lt;\/p&gt;\n&lt;p&gt;If your doctor determines Opdivo for mesothelioma is not effective in your case, they can help you explore other treatment options.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"What are the long-term side effects of Opdivo?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;You may experience a number of side effects while being treated with Opdivo.&lt;\/p&gt;\n&lt;p&gt;&lt;strong&gt;Long-term Opdivo side effects include:&lt;\/strong&gt;&lt;\/p&gt;\n&lt;ul class=&quot;columns-2&quot;&gt;\n&lt;li&gt;Arthralgia (joint pain) and myalgia (muscle pain)&lt;\/li&gt;\n&lt;li&gt;Colitis (inflammation of the colon)&lt;\/li&gt;\n&lt;li&gt;Diarrhea&lt;\/li&gt;\n&lt;li&gt;Hepatitis (liver inflammation)&lt;\/li&gt;\n&lt;li&gt;Kidney problems&lt;\/li&gt;\n&lt;li&gt;Nervous system issues&lt;\/li&gt;\n&lt;li&gt;Pneumonitis (lung inflammation)&lt;\/li&gt;\n&lt;li&gt;Skin issues (rash or pruritus)&lt;\/li&gt;\n&lt;li&gt;Thyroid disorders (hypothyroidism or hyperthyroidism)&lt;\/li&gt;\n&lt;\/ul&gt;\n&lt;p&gt;You may experience side effects because Opdivo stimulates T cells, which could attack healthy organs and cells while working to kill mesothelioma cells.&lt;\/p&gt;\n\"}}]}<\/script><style type=\"text\/css\">.faq-wrap{background:#E4F4F6;padding:20px 15px;margin:40px -15px}.faq-wrap:first-child{margin-top:0}.faq-wrap:last-child{margin-bottom:0}.faq-wrap .faq{background:#fff;padding:15px;border-radius:10px;box-shadow:0px 20px 20px rgba(0,0,0,0.03);margin:15px 0 0 0}.faq-wrap .faq:first-child{margin-top:0}.faq-wrap .faq .faq-heading{color:#100134;font-size:21px;margin-bottom:15px}.faq-wrap .faq p{margin-bottom:20px;line-height:1.5}.faq-wrap .faq p:last-child{margin-bottom:0}.faq-wrap .faq .learn-more{color:#248AFF;display:block;padding-right:17px;text-align:right;position:relative;line-height:1}.faq-wrap .faq .learn-more:visited{color:#248AFF}.faq-wrap .faq .learn-more:visited:hover,.faq-wrap .faq .learn-more:hover{color:#34d}.faq-wrap .faq .learn-more:after{font-family:\"mesohope\" !important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e905\";position:absolute;right:0;top:3px}h2.faq-wrap-heading{margin-bottom:25px}@media screen and (min-width: 768px){.faq-wrap{padding:25px 15px}}@media screen and (min-width: 1024px){.faq-wrap{border-radius:10px;margin-left:auto;margin-right:auto;padding:25px}.faq-wrap .faq{padding:25px}.faq-heading{font-size:24px}}<\/style><\/div>\n","protected":false},"excerpt":{"rendered":"<p>What Is Opdivo? Opdivo (generic name nivolumab) is one of the first immunotherapy drugs approved for pleural mesothelioma, along with Yervoy (generic name ipilimumab). In October 2020, the U.S. Food and Drug Administration (FDA) approved the combination of Opdivo and Yervoy for pleural mesothelioma patients who aren\u2019t eligible for surgery. Prior to this, both drugs&hellip;<\/p>\n","protected":false},"author":49,"featured_media":0,"parent":768,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-22851","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/22851","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/comments?post=22851"}],"version-history":[{"count":0,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/22851\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/768"}],"wp:attachment":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media?parent=22851"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}