{"id":23777,"date":"2024-03-21T13:30:49","date_gmt":"2024-03-21T17:30:49","guid":{"rendered":"https:\/\/www.mesotheliomahope.com\/?page_id=23777"},"modified":"2025-09-15T16:30:22","modified_gmt":"2025-09-15T20:30:22","slug":"dr-jeffrey-clarke","status":"publish","type":"page","link":"https:\/\/www.mesotheliomahope.com\/treatment\/doctors\/dr-jeffrey-clarke\/","title":{"rendered":"Dr. Jeffrey Clarke"},"content":{"rendered":"<h2>About Dr. Jeffrey Clarke<\/h2>\n<p>Dr. Jeffrey Clarke is an oncologist at Duke Cancer Center in Durham, North Carolina, where he treats patients diagnosed with <a href=\"\/mesothelioma\/\">mesothelioma<\/a>, lung cancer, and brain and spinal tumors.<\/p>\n<p>He also serves as the Associate Co-Director of Cell-Based Immunotherapy for Duke Cancer Center\u2019s thoracic cancer disease group.<\/p>\n<blockquote><p>\u201cWorking closely with my patients \u2014 getting to know them and understanding their values and goals \u2014 allows me to develop individualized care and treatment.\u201d<br \/>\n<strong>\u2013 Dr. Jeffrey Clarke, pleural mesothelioma specialist<\/strong><\/p><\/blockquote>\n<p>With a profound understanding of mesothelioma, Dr. Clarke develops personalized treatment plans based on each patient\u2019s specific needs.<\/p>\n<p>Find top mesothelioma specialists like Dr. Clarke near you with our <strong>Free Doctor Match.<\/strong><\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>Dr. Jeffrey Clarke\u2019s Mesothelioma Treatment Approach<\/h2>\n<p>Dr. Jeff Clarke takes a multimodal approach to <a href=\"\/treatment\/\">mesothelioma treatment<\/a>, incorporating two or more treatment methods to most effectively fight this cancer.<\/p>\n<p>He believes in using a combination of therapies tailored to each patient&#8217;s specific needs but is particularly experienced with <a href=\"\/treatment\/immunotherapy\/\">immunotherapy for mesothelioma<\/a>. Dr. Clarke also explores novel therapies and new combinations of existing treatments in clinical trials.<\/p>\n<p>He is a compassionate doctor who fosters communication and understanding with his patients, ensuring they are fully informed and supported throughout treatment.<\/p>\n<blockquote><p>\u201cThe most rewarding part of my work is developing long-term relationships with my patients and their families throughout their cancer journeys.\u201d<br \/>\n<strong>\u2013 Dr. Jeffrey Clarke, pleural mesothelioma specialist<\/strong><\/p><\/blockquote>\n<h2>Dr. Jeffrey Clarke\u2019s Medical Specializations<\/h2>\n<p>As a seasoned medical oncologist, Dr. Clarke treats pleural mesothelioma and a wide range of other diseases and cancers using advanced treatment methods.<\/p>\n<p><strong>His medical specialties include:<\/strong><\/p>\n<\/p>\n<ul class='columns-2'>\n<li>Lung cancer<\/li>\n<li><a href=\"\/mesothelioma\/pleural\/\">Pleural mesothelioma<\/a> (cancer of the lung lining)<\/li>\n<li>Metastatic brain and spine tumors<\/li>\n<li>Immunotherapy<\/li>\n<li><a href=\"\/treatment\/targeted-therapies\/\">Targeted therapy<\/a><\/li>\n<\/ul>\n<p>\n<p>Download our <strong>Free Questions to Ask Your Doctor Checklist<\/strong> to get answers about your diagnosis and treatment plan during your next appointment.<\/p>\n<div data-vqueid=\"18575\" class=\"widget widget_oscar-vque outline image-left has-img\"><style type=\"text\/css\" data-style=\"outline\">.widget_oscar-vque.outline{margin:60px auto;max-width:315px}.widget_oscar-vque.outline:first-child{margin-top:0}.widget_oscar-vque.outline:last-child{margin-bottom:0}.widget_oscar-vque.outline>a{border:1px solid #E6E7EC;padding:20px;box-shadow:0 20px 20px rgba(34,34,34,0.03);border-radius:10px;color:#383441;display:block;text-decoration:none}.widget_oscar-vque.outline img{margin:0 auto 20px;max-width:180px}.widget_oscar-vque.outline .vque-content{color:#383441;font-size:16px;text-align:center}.widget_oscar-vque.outline strong.subheading{color:#100134;display:block;line-height:1;font-size:14px;margin-bottom:5px}.widget_oscar-vque.outline strong.heading{color:#100134;font-size:20px;display:block;margin:0 0 20px}.widget_oscar-vque.outline ul{font-size:16px;text-align:left;list-style:none;max-width:265px;margin:15px auto 25px}.widget_oscar-vque.outline ul li{padding-left:28px;margin-bottom:10px}.widget_oscar-vque.outline ul li:last-child{margin-bottom:0}.widget_oscar-vque.outline ul li:before{font-family:\"mesohope\" !important;font-display:swap;speak:none;color:#fff;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e904\";border:none;position:absolute;left:0;top:3px;background:#0FAEBF;width:20px;height:20px;border-radius:20px;line-height:20px;text-align:center;font-size:12px}.widget_oscar-vque.outline strong.button.arrow{width:100%}.widget_oscar-vque.outline.image-left>a{position:relative;border-radius:0 10px 10px 0}.widget_oscar-vque.outline.image-left>a:before{content:\" \";position:absolute;top:0;bottom:0;width:4px;height:100%;left:0;background:linear-gradient(180deg, #0FAEBF 0%, #fff 100%)}@media screen and (min-width: 768px){.widget_oscar-vque.outline{max-width:620px}.widget_oscar-vque.outline img{max-width:100%}.widget_oscar-vque.outline>a{padding:0}.widget_oscar-vque.outline>a>div{display:block;display:flex;flex-wrap:wrap;align-items:flex-end;flex-direction:row-reverse}.widget_oscar-vque.outline>a>div>div{width:41%}.widget_oscar-vque.outline>a .vque-content{width:59%;padding:30px;text-align:left}.widget_oscar-vque.outline strong.subheading{font-size:16px}.widget_oscar-vque.outline strong.heading{font-size:24px;margin:0 0 13px}.widget_oscar-vque.outline ul{max-width:none}.widget_oscar-vque.outline strong.button.arrow{width:auto}.widget_oscar-vque.outline.image-left>a>div{display:block;position:relative;overflow:hidden}.widget_oscar-vque.outline.image-left>a>div>div{float:left}.widget_oscar-vque.outline.image-left>a>div>div:first-child{width:27%;padding:30px}.widget_oscar-vque.outline.image-left>a>div>div.vque-content{width:73%;padding-left:0;color:#383441}}<\/style><a href=\"\/doctor-questions\/\" title=\"Free Download: 14 Questions to Ask\u00a0Your Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Free Download: 14 Questions to Ask\u00a0Your Doctor Ad\" data-desktop-image=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2021\/05\/questions-to-ask-doctor-ipad.png\"><div><div><img loading=\"lazy\" decoding=\"async\" width=\"95\" height=\"144\" src=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2021\/05\/questions-to-ask-doctor-ipad.png\" class=\"attachment-Medium size-Medium wp-post-image\" alt=\"14 Questions to Ask Your Doctor packet\" \/><\/div><div class=\"vque-content\"><strong class=\"heading\">Free Download: 14 Questions to Ask\u00a0Your Doctor<\/strong><ul>\n<li>Preparing for treatment<\/li>\n<li>Finding clinical trials<\/li>\n<li>Getting a second opinion<\/li>\n<\/ul>\n<p><strong class=\"button yellow arrow\" title=\"Get Your Free Download\">Get Your Free Download<\/strong><\/p><\/div><\/div><\/a><\/div>\n<h2>Dr. Jeffrey Clarke\u2019s Medical Background<\/h2>\n<p>Dr. Clarke earned his medical degree from the Indiana University School of Medicine in 2008. He completed a residency in internal medicine at Duke University Medical Center in 2011, followed by a fellowship in medical oncology at the same institution in 2015.<\/p>\n<p>In addition to seeing patients at <a href=\"\/cancer-centers\/duke-cancer-center\/\">Duke Cancer Center<\/a>, Dr. Clarke holds positions as an associate professor of medicine in medical oncology at the Duke University School of Medicine and a member of the Duke Cancer Center, reflecting his commitment to professional education and cancer research.<\/p>\n<p>With over a decade of experience in oncology, Dr. Clarke has dedicated his career to advancing cancer treatment. He\u2019s also played a pivotal role in clinical trials for mesothelioma and <a href=\"\/cancer\/lung-cancer\/\">lung cancer<\/a>.<\/p>\n<h2>Highlights of Dr. Jeffrey Clarke\u2019s Professional Career<\/h2>\n<p>Throughout his career, Dr. Clarke has garnered recognition for his exceptional work in the field of oncology.<\/p>\n<h3>Appointments and Accolades<\/h3>\n<p>Dr. Clarke&#8217;s professional and academic contributions have led him to be recognized by both the Duke University Health System and the Duke University School of Medicine.<\/p>\n<p><strong>These recognitions include:<\/strong><\/p>\n<ul>\n<li>Appointment as Associate Professor of Medicine in Medical Oncology<\/li>\n<li>Membership in the Duke Cancer Center<\/li>\n<li>Recognition for Excellence in Patient Care<\/li>\n<\/ul>\n<h3>Professional Affiliations<\/h3>\n<p>Dr. Clarke holds several licenses and affiliations related to internal medicine and medical oncology.<\/p>\n<p><strong>These affiliations include:<\/strong><\/p>\n<ul>\n<li>Board certification in medical oncology by the American Board of Internal Medicine<\/li>\n<li>Board certification in internal medicine by the American Board of Internal Medicine<\/li>\n<li>North Carolina State Medical License<\/li>\n<\/ul>\n<p>According to Duke&#8217;s official site, Dr. Clarke has an <strong>overall rating of 4.8 out of 5<\/strong> from patients, indicating that he consistently exceeds their expectations.<\/p>\n<h2>Dr. Jeffrey Clarke\u2019s Published Works<\/h2>\n<p>Dr. Clarke&#8217;s dedication to advancing treatment is evident in his extensive cancer research and publications.<\/p>\n<p><strong>Some of his most recent published works include:<\/strong><\/p>\n<ul>\n<li>&#8220;Updated Efficacy and Safety From the Phase 2 PHAROS Study of Encorafenib Plus Binimetinib in Patients With BRAF V600E-Mutant Metastatic NSCLC\u2012A Brief Report.&#8221; Published in\u00a0<em>TheJournal of Thoracic Oncology,\u00a0<\/em>June 2025.<\/li>\n<li>\u201cLong-term Intracranial Outcomes with Combination Dual Immune-Checkpoint Blockade and SRS in Patients with Melanoma and NSCLC Brain Metastases.\u201d Published in the <em>International Journal of Radiation Oncology, Biology, Physics,<\/em> December 2023.<\/li>\n<li>\u201cT-cell responses to individualized neoantigen therapy (INT) mRNA-4157 (V940) as monotherapy or in combination with pembrolizumab.\u201d Published in <em>The Journal for ImmunoTherapy of Cancer<\/em>, October 2023.<\/li>\n<li>\u201cResults from a first-in-human phase 1B study of a complement factor H inhibitor (GT103) in patients with non-small cell lung cancer (NSCLC).\u201d Published in the <em>Journal of Clinical Oncology<\/em>, June 2023.<\/li>\n<li>\u201cSocioeconomic disparities in immunotherapy use among advanced-stage non-small cell lung cancer patients: analysis of the National Cancer Database.\u201d Published in <em>Scientific Reports<\/em>, May 2023.<\/li>\n<\/ul>\n<p>By pushing the boundaries of cancer research, Dr. Clarke is helping advance the field of oncology and providing hope to those affected by mesothelioma.<\/p>\n<p>Use our <strong>Free Doctor Match<\/strong> now to connect with leading mesothelioma experts like Dr. Clarke in your area.<\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>Dr. Jeffrey Clarke\u2019s Work in Cancer Treatment and Research<\/h2>\n<p>Dr. Clarke\u2019s contributions to <a href=\"\/treatment\/clinical-trials\/\">clinical trials,<\/a> particularly in investigating novel treatments for lung cancer and mesothelioma, have shown to help patients live longer after a diagnosis.<\/p>\n<p>His research efforts have also contributed to developing personalized treatment strategies, such as immunotherapy to target cancer cells more effectively.<\/p>\n<p>Dr. Clarke is currently working with other mesothelioma doctors on a clinical trial testing the combination of surgery and immunotherapy in patients with sarcomatoid mesothelioma. This is the most aggressive <a href=\"\/mesothelioma\/cell-types\/\">mesothelioma cell type<\/a>.<\/p>\n<h2>Get Connected to Dr. Jeffrey Clarke<\/h2>\n<p>If you or a loved one are seeking specialized care for mesothelioma in the Raleigh-Durham area, Dr. Clarke is currently accepting new patients at Duke Cancer Center.<\/p>\n<p>His expertise in mesothelioma treatment, coupled with his patient-centered approach, ensures you\u2019ll receive the personalized care and attention you deserve.<\/p>\n<blockquote><p>\u201cDuke is a remarkable place where world-class people come together with the common goal of trying to provide the very best exceptional care to patients and their families, and doing so in a comprehensive way.\u201d<br \/>\n<strong>\u2013 Dr. Jeffrey Clarke, pleural mesothelioma specialist<\/strong><\/p><\/blockquote>\n<p>Mesothelioma Hope can help you connect with Dr. Clarke and other top mesothelioma specialists right now. Call <a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a> or use our <a href=\"\/get-matched\/\">Free Doctor Match<\/a> to get started.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>About Dr. Jeffrey Clarke Dr. Jeffrey Clarke is an oncologist at Duke Cancer Center in Durham, North Carolina, where he treats patients diagnosed with mesothelioma, lung cancer, and brain and spinal tumors. He also serves as the Associate Co-Director of Cell-Based Immunotherapy for Duke Cancer Center\u2019s thoracic cancer disease group. \u201cWorking closely with my patients&hellip;<\/p>\n","protected":false},"author":49,"featured_media":23778,"parent":49,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/template-doctor.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-23777","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/23777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/comments?post=23777"}],"version-history":[{"count":0,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/23777\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/49"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media\/23778"}],"wp:attachment":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media?parent=23777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}