{"id":24443,"date":"2024-09-19T00:00:00","date_gmt":"2024-09-19T04:00:00","guid":{"rendered":"https:\/\/www.mesotheliomahope.com\/?p=24443"},"modified":"2024-10-12T15:27:15","modified_gmt":"2024-10-12T19:27:15","slug":"fda-approval-of-keytruda-mesothelioma-treatment","status":"publish","type":"post","link":"https:\/\/www.mesotheliomahope.com\/blog\/fda-approval-of-keytruda-mesothelioma-treatment\/","title":{"rendered":"Keytruda Gets FDA Approval for Initial Treatment of Pleural Mesothelioma"},"content":{"rendered":"<p>On September 17, the U.S. Food and Drug Administration (FDA) approved <a href=\"\/treatment\/immunotherapy\/keytruda\/\">pembrolizumab (Keytruda\u00ae)<\/a> with chemotherapy as a standard treatment for certain cases of mesothelioma. This news came a week earlier than projected after the FDA&#8217;s May 29 announcement that it had prioritized its review of Keytruda for mesothelioma patients who cannot have surgery.<\/p>\n<p>Keytruda is an <a href=\"\/treatment\/immunotherapy\/\">immunotherapy drug<\/a> that works by blocking PD-1, a protein that immune T cells use to determine which cells are good and bad. This helps them kill cancer cells that try to hide from the immune system.<\/p>\n<blockquote><p>\u201cWe\u2019re pleased to offer a <strong>new first-line treatment option<\/strong> for adult patients with unresectable advanced or metastatic malignant pleural mesothelioma,\u201d said Dr. Gregory Lubiniecki, vice president of oncology clinical research for Merck Research Laboratories. \u201cThis milestone underscores our commitment to advancing research <strong>for patients with difficult-to-treat tumors<\/strong>.\u201d<\/p><\/blockquote>\n<p>With Keytruda\u2019s approval by the FDA, mesothelioma patients will now have access to another treatment method that could help them live longer.<\/p>\n<p>Download our <strong>Free Immunotherapy Guide<\/strong> to learn more about the benefits of Keytruda and other immunotherapy drugs for <a href=\"\/mesothelioma\/\">mesothelioma<\/a>.<\/p>\n<div id=\"23756\" class=\"one-off-23756 widget widget_oscar-vque one-off\" data-vqueid=\"23756\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-23756{margin:60px auto}.one-off-23756 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:linear-gradient(90deg,#B1E5EA 0,#0FAEBF 100%);padding:20px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:350px;margin:0 auto}.one-off-23756 a::before{background:#EDF8F9;border-radius:0 0 50% 50%;content:'';position:absolute;top:0;height:87%;width:140%;left:-70px;z-index:0}.one-off-23756 .vque-content,.one-off-23756 .image-wrap{z-index:1;position:relative}.one-off-23756 .image-wrap{max-width:163px;display:block;margin:15px auto -21px}.one-off-23756 .heading{font-size:24px;line-height:28px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-23756 ul{max-width:160px;list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:27px}.one-off-23756 ul li{margin:0;position:relative;padding-left:28px}.one-off-23756 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:14px;height:14px;display:block;position:absolute;left:0;top:7px;border-radius:50%;color:#fff;font-size:7px;text-align:center;line-height:14px}.one-off-23756 p{text-align:center}.one-off-23756 .button{padding:12px 16px}@media screen and (min-width:768px){.one-off-23756 a{max-width:620px;padding:25px 50px 29px;border-radius:0 0 4px 4px}.one-off-23756 a::before{border-radius:0 0 100% 0;height:83%;width:70%;right:-70px;left:unset}.one-off-23756 a::after{background:#EDF8F9;border-radius:0;content:'';position:absolute;top:0;height:82%;width:50%;left:0;z-index:0}.one-off-23756 .heading{text-align:left;margin:5px 0 25px}.one-off-23756 ul{margin:-10px 0 22px}.one-off-23756 .image-wrap{max-width:unset;position:absolute;right:0;bottom:0;margin:0 0 -2px}.one-off-23756 p{text-align:left}}<\/style><a href=\"\/immunotherapy-guide\/\" title=\"Get Your Free Immunotherapy Guide\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Your Free Immunotherapy Guide Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Your Free Immunotherapy Guide<\/strong>\r\n        <ul>\r\n            <li>When it\u2019s used<\/li>\r\n            <li>Types of drugs<\/li>\r\n            <li>Side effects<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Your Free Guide\">Get Your Free Guide<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/03\/download-immunotherapy-guide.png\" alt=\"Free Immunotherapy Guide\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>About KEYNOTE-483: Keytruda Mesothelioma Clinical Trial<\/h2>\n<p>The FDA approved Keytruda based on the results of a recent <a href=\"\/treatment\/clinical-trials\/\">clinical trial<\/a> known as IND.227\/KEYNOTE-483.<\/p>\n<p>In the KEYNOTE-483 trial, 440 patients with advanced, inoperable pleural mesothelioma received either Keytruda and chemotherapy or chemotherapy alone.<\/p>\n<p>Those who were given Keytruda with chemotherapy had <strong>significantly improved survival<\/strong> compared to those who received only <a href=\"\/treatment\/chemotherapy\/\">chemotherapy<\/a>.<\/p>\n<p><strong>When treated with Keytruda and chemotherapy, patients had a:<\/strong><\/p>\n<ul>\n<li>3-year survival rate of 25%, while the 3-year <a href=\"\/mesothelioma\/prognosis\/survival-rate\/\">survival rate<\/a> with chemotherapy alone was 17%<\/li>\n<li>21% reduced risk of death<\/li>\n<li>Response rate of 62%, compared to just 38% of the control group<\/li>\n<\/ul>\n<p>In addition, patients who received Keytruda and chemotherapy had a slightly longer life expectancy and experienced fewer <a href=\"\/blog\/managing-mesothelioma-immunotherapy-side-effects\/\">immunotherapy side effects<\/a> than those who received chemotherapy alone.<\/p>\n<div class=\"blockquote-w-image \"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/07\/jenna-tozzi-small.jpg\" alt=\"\" \/><blockquote><p>&#8220;Immunotherapy has shown promise in supporting mesothelioma patients by boosting the immune system to recognize and fight cancer cells. It\u2019s like giving your body an extra set of tools to combat the disease more effectively.&#8221;<\/p>\n<footer>&ndash;<cite> Jenna Tozzi, RN, Chief Patient Care Advisor for Mesothelioma Hope<\/cite><\/footer><\/blockquote><style type=\"text\/css\">.blockquote-w-image{position:relative;margin:40px auto}.blockquote-w-image blockquote{background:none;border-left:none;padding:25px;margin-top:0;padding-bottom:0;font-size:inherit;line-height:inherit}.blockquote-w-image blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote p{margin-bottom:0}.blockquote-w-image img{width:100px;border:none;border-radius:100%;box-shadow:none;position:relative;margin:0 auto}.blockquote-w-image.alternative{margin:60px auto}.blockquote-w-image.alternative blockquote{padding:25px 25px 25px 80px;padding-bottom:25px;background-color:#E4F4F6}.blockquote-w-image.alternative img{position:absolute;left:20px;top:25px;z-index:1;width:50px;border:1px solid #fff;box-shadow:0 0 10px rgba(34,34,34,0.2);border-radius:100%}.blockquote-w-image.with-border{background:none;border-left:4px solid #0FAEBF}.blockquote-w-image.with-border blockquote{background:none;border-radius:0;padding:10px 25px}.blockquote-w-image.with-border blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote:before{display:none}@media screen and (min-width: 769px){.blockquote-w-image img{position:absolute;left:0;top:0}.blockquote-w-image blockquote{padding:0 25px 0 125px;min-height:90px}}@media screen and (min-width: 1024px){.blockquote-w-image.alternative blockquote{padding-left:105px}.blockquote-w-image.alternative blockquote footer cite{font-size:16px}.entry-content .blockquote-w-image.alternative img{width:60px;left:25px}}<\/style><\/div>\n<p>Use our <strong>Free Doctor Match<\/strong> to find mesothelioma specialists who can help you access Keytruda and other immunotherapies.<\/p>\n<h2>What Does the FDA\u2019s Approval of Keytruda Mean for Mesothelioma Patients?<\/h2>\n<p>The FDA\u2019s approval of Keytruda for mesothelioma is a significant development in cases where <a href=\"\/treatment\/surgery\/\">surgery<\/a> isn&#8217;t possible.<\/p>\n<p>This is very encouraging, as Keytruda may give pleural mesothelioma patients with inoperable cancer another potentially more effective treatment option.<\/p>\n<blockquote><p>\u201c<a href=\"\/mesothelioma\/pleural\/\">Malignant pleural mesothelioma<\/a> is typically diagnosed in advanced stages when curative surgery is not an option and progresses quickly,\u201d explained Dr. Lubiniecki. &#8220;Given the aggressive nature of pleural mesothelioma, Keytruda could provide <strong>a much-needed lifeline and set a new standard of care<\/strong> for those affected by this rare cancer.&#8221;<\/p><\/blockquote>\n<h2>Find Keytruda Mesothelioma Treatment Now<\/h2>\n<p>Mesothelioma Hope\u2019s team of Patient Advocates is dedicated to helping patients get the medical and financial support they need after a diagnosis.<\/p>\n<p>We can help you pursue Keytruda or other immunotherapies and <a href=\"\/treatment\/\">treatments<\/a> that could improve your survival.<\/p>\n<div class=\"blockquote-w-image \"><img decoding=\"async\" src=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2023\/02\/amy-fair-nurse.png\" alt=\"\" \/><blockquote><p>&#8220;Answering patient questions, explaining options, and sometimes just listening to a patient and their loved one is the number one reason why I\u2019m here.&#8221;<\/p>\n<footer>&ndash;<cite> Amy Fair, RN, Mesothelioma Hope Patient Advocate<\/cite><\/footer><\/blockquote><style type=\"text\/css\">.blockquote-w-image{position:relative;margin:40px auto}.blockquote-w-image blockquote{background:none;border-left:none;padding:25px;margin-top:0;padding-bottom:0;font-size:inherit;line-height:inherit}.blockquote-w-image blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote p{margin-bottom:0}.blockquote-w-image img{width:100px;border:none;border-radius:100%;box-shadow:none;position:relative;margin:0 auto}.blockquote-w-image.alternative{margin:60px auto}.blockquote-w-image.alternative blockquote{padding:25px 25px 25px 80px;padding-bottom:25px;background-color:#E4F4F6}.blockquote-w-image.alternative img{position:absolute;left:20px;top:25px;z-index:1;width:50px;border:1px solid #fff;box-shadow:0 0 10px rgba(34,34,34,0.2);border-radius:100%}.blockquote-w-image.with-border{background:none;border-left:4px solid #0FAEBF}.blockquote-w-image.with-border blockquote{background:none;border-radius:0;padding:10px 25px}.blockquote-w-image.with-border blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote:before{display:none}@media screen and (min-width: 769px){.blockquote-w-image img{position:absolute;left:0;top:0}.blockquote-w-image blockquote{padding:0 25px 0 125px;min-height:90px}}@media screen and (min-width: 1024px){.blockquote-w-image.alternative blockquote{padding-left:105px}.blockquote-w-image.alternative blockquote footer cite{font-size:16px}.entry-content .blockquote-w-image.alternative img{width:60px;left:25px}}<\/style><\/div>\n<p>Call us now at <a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a> or download our <a href=\"\/immunotherapy-guide\/\">Free Immunotherapy Guide<\/a> to get started.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>On September 17, the U.S. Food and Drug Administration (FDA) approved pembrolizumab (Keytruda\u00ae) with chemotherapy as a standard treatment for certain cases of mesothelioma. This news came a week earlier than projected after the FDA&#8217;s May 29 announcement that it had prioritized its review of Keytruda for mesothelioma patients who cannot have surgery. Keytruda is&hellip;<\/p>\n","protected":false},"author":35,"featured_media":24449,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[118],"tags":[278,67,82,169,279],"class_list":["post-24443","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mesothelioma-treatment","tag-keytruda-for-mesothelioma","tag-mesothelioma","tag-mesothelioma-immunotherapy","tag-mesothelioma-treatment","tag-pembrolizumab-for-mesothelioma"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/posts\/24443","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/users\/35"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/comments?post=24443"}],"version-history":[{"count":0,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/posts\/24443\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media\/24449"}],"wp:attachment":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media?parent=24443"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/categories?post=24443"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/tags?post=24443"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}