{"id":26076,"date":"2024-11-01T16:12:28","date_gmt":"2024-11-01T20:12:28","guid":{"rendered":"https:\/\/www.mesotheliomahope.com\/?page_id=26076"},"modified":"2025-12-23T17:19:45","modified_gmt":"2025-12-23T22:19:45","slug":"pipac","status":"publish","type":"page","link":"https:\/\/www.mesotheliomahope.com\/treatment\/chemotherapy\/pipac\/","title":{"rendered":"PIPAC for Mesothelioma"},"content":{"rendered":"<h2>What Is PIPAC for Mesothelioma?<\/h2>\n<p>PIPAC is an innovative approach for treating malignant <a href=\"\/treatment\/peritoneal\/\">peritoneal mesothelioma<\/a>. It involves turning chemotherapy into a high-pressure aerosol mist and delivering it directly into the abdominal cavity (peritoneum), which helps cancer-fighting drugs better penetrate tumor tissue.<\/p>\n<p>PIPAC for mesothelioma is currently only available in clinical trials, where it\u2019s showing promise in managing cancer symptoms and improving quality of life.<\/p>\n<h4><strong>Key Facts on PIPAC Treatment<\/strong><\/h4>\n<ul>\n<li>Doctors recommend several PIPAC cycles for the best outcome.<\/li>\n<li>A 2021 study found that patients who received PIPAC, cytoreductive surgery, and heated intraperitoneal chemotherapy (HIPEC) lived <strong>33.5 months<\/strong> on average.<\/li>\n<li>PIPAC generally has fewer side effects than cytoreductive surgery with HIPEC.<\/li>\n<\/ul>\n<p>As studies continue, PIPAC could one day become a standard <a href=\"\/treatment\/\">treatment option<\/a> for peritoneal mesothelioma. Download our <strong>Free Chemotherapy Guide<\/strong> to learn about the top cancer drugs for mesothelioma, what to expect, and how to manage side effects.<\/p>\n<div id=\"28840\" class=\"one-off-28840 widget widget_oscar-vque one-off\" data-vqueid=\"28840\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-28840{margin:60px auto;max-width:335px}.one-off-28840:first-child{margin-top:0}.one-off-28840:last-child{margin-bottom:0}.one-off-28840>a{background:#2F293D;display:block;padding:20px;padding-bottom:35px;border-radius:10px;color:#fff;text-decoration:none}.one-off-28840 img.mobile-only{margin:0 auto 20px;max-width:177px;width:100%}.one-off-28840 img:not(.mobile-only){display:none}.one-off-28840 .vque-content{font-size:16px;text-align:center}.one-off-28840 strong.heading{font-size:24px;display:block;margin:0}.one-off-28840 .subheading{font-size:14px}.one-off-28840 ul{font-size:16px;text-align:left;list-style:none;max-width:265px;line-height:1.4;margin:15px auto 25px}.one-off-28840 ul li{padding-left:28px;margin-bottom:15px}.one-off-28840 ul li:last-child{margin-bottom:0}.one-off-28840 ul li:before{font-family:\"mesohope\"!important;line-height:1;content:\"\\e904\";border:0;position:absolute;left:0;top:0;background:#0FAEBF;width:20px;height:20px;border-radius:20px;line-height:20px;text-align:center;font-size:12px}@media screen and (min-width:768px){.one-off-28840{max-width:620px}.one-off-28840>a{padding:0;background:linear-gradient(90.42deg,#2F293D 51.6%,#4A415F 109.35%)}.one-off-28840>a>div{display:block;display:flex;align-items:end;flex-wrap:wrap;position:relative}.one-off-28840 .vque-content{width:65%;padding:30px;text-align:left}.one-off-28840 img.mobile-only{display:none}.one-off-28840 img:not(.mobile-only){display:block;width:250px;margin-bottom:0;position:absolute;bottom:0;right:0}.one-off-28840 ul{max-width:none}.one-off-28840 ul li{margin-bottom:10px}}<\/style><a href=\"\/chemotherapy-guide\/\" title=\"Free Chemotherapy Guide\u2028for Mesothelioma Patients\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Free Chemotherapy Guide\u2028for Mesothelioma Patients Ad\"><div>\r\n<div>\r\n<div class=\"image-fade\">\r\n<img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/07\/thank-you-page-chemotherapy-img.png\" alt=\"Chemotherapy Guide Images\" class=\"mobile-only\">\r\n<img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/07\/chemo-guide-img.png\" alt=\"Chemotherapy Guide Images\">\r\n<\/div>\r\n<\/div>\r\n<div class=\"vque-content\">\r\n<strong class=\"heading\">Free Chemotherapy Guide\u2028for Mesothelioma Patients<\/strong>\r\n<span class=\"subheading\">Written by cancer nurses<\/span>\r\n<ul>\r\n<li>Top chemo drugs explained<\/li>\r\n<li>Preparing for your first session<\/li>\r\n<li>Managing side effects like\u2028nausea & fatigue<\/li>\r\n<\/ul>\r\n<p><strong class=\"button arrow\" title=\"Download It Now\">Download It Now<\/strong><\/p><\/div><\/div><\/a><\/div>\n<h2>How Does the PIPAC Procedure Work for Mesothelioma?<\/h2>\n<p>PIPAC delivers concentrated <a href=\"\/treatment\/chemotherapy\/\">mesothelioma chemotherapy<\/a> directly into the peritoneum through a pump system that sprays the liquid cancer-fighting drugs across the cavity. This allows doctors to target cancer cells more effectively than traditional chemotherapy, which circulates throughout the body in a less concentrated dose.<\/p>\n<h3>What to Expect During PIPAC Cancer Treatment Sessions<\/h3>\n<ol>\n<li><strong>Receive anesthesia:<\/strong> You\u2019ll undergo general anesthesia, so you won\u2019t feel any pain during the treatment.<\/li>\n<li><strong>Get PIPAC surgery:<\/strong> PIPAC is a laparoscopic procedure, meaning doctors make small surgical incisions to insert the pump into the abdomen.<\/li>\n<li><strong>Undergo chemotherapy:<\/strong> The <a href=\"\/treatment\/chemotherapy\/drugs\/\">chemotherapy drugs<\/a> are administered as an aerosol mist, which allows the drugs to spread throughout the abdomen and penetrate tumors. This takes about 60-90 minutes.<\/li>\n<li><strong>Recover in the hospital:<\/strong> After the procedure, you may need to stay in the hospital for 1-2 days. Doctors can monitor you for any possible complications and recommend follow-up care if needed.<\/li>\n<\/ol>\n<p>You can get multiple cycles of PIPAC for mesothelioma, depending on your doctor&#8217;s recommendation.<\/p>\n<p>Most medical teams suggest getting a <strong>minimum of 3 PIPAC cycles<\/strong> for best results, according to a 2023 report in <em>PLOS One<\/em>. If you don\u2019t experience severe side effects and PIPAC helps to shrink your cancer tumors, you can potentially receive over a dozen cycles.<\/p>\n<h2>HIPEC vs. PIPAC for Mesothelioma<\/h2>\n<p>PIPAC and <a href=\"\/treatment\/surgery\/cytoreduction-hipec\/\">cytoreduction with HIPEC<\/a> are unique treatments that may help peritoneal mesothelioma patients live longer. While both treatments deliver chemotherapy directly into the abdomen, they differ in how invasive they are, when they\u2019re used, and which patients may benefit most.<\/p>\n<div class=\"table-wrap \">\n<table id=\"tablepress-95\" class=\"tablepress tablepress-id-95\">\n<thead>\n<tr class=\"row-1\">\n\t<th class=\"column-1\">PIPAC<\/th><th class=\"column-2\">Cytoreduction With HIPEC<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">Only available in clinical trials<\/td><td class=\"column-2\">More widely available as a standard treatment<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">Minimally invasive chemotherapy<\/td><td class=\"column-2\">Major surgery and chemotherapy treatment<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">Patients can leave the hospital in 1-2 days<\/td><td class=\"column-2\">Patients may need up to 2 weeks in the hospital to recover<\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">Takes less than 2 hours<\/td><td class=\"column-2\">Takes 4-10 hours<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><!-- #tablepress-95 from cache -->\n<p>Understanding the differences between <a href=\"\/treatment\/chemotherapy\/pipac-vs-hipec\/\">PIPAC vs. HIPEC for mesothelioma<\/a> can help patients and families make more informed treatment decisions with their care team. Doctors may recommend cytoreduction with HIPEC and PIPAC as part of mesothelioma treatment plans if the patient is healthy enough.<\/p>\n<h2>Benefits of PIPAC Cancer Treatment<\/h2>\n<p>PIPAC has several potential benefits in <a href=\"\/treatment\/peritoneal\/\">treating peritoneal mesothelioma<\/a>.<\/p>\n<p><strong>The advantages of PIPAC for mesothelioma include:<\/strong><\/p>\n<ul>\n<li><strong>Access to surgery:<\/strong> In a 2022 study published in <em>The Annals of Surgical Oncology<\/em>, PIPAC shrank cancer tumors to the point where 55% of peritoneal mesothelioma patients qualified for tumor-removing surgery. Before PIPAC, their cancer was considered unresectable (not treatable with surgery).<\/li>\n<li><strong>Higher chemotherapy concentration:<\/strong> PIPAC delivers a high dose of chemotherapy directly to the tumor site, attacking cancer cells while minimizing harm to healthy tissue.<\/li>\n<li><strong>Minimized side effects:<\/strong> Since PIPAC uses lower doses of chemotherapy and is a minimally invasive procedure, it has fewer side effects compared to traditional chemotherapy or cytoreduction with HIPEC.<\/li>\n<li><strong>Extended survival:<\/strong> When combined with other treatments like cytoreduction with HIPEC, peritoneal mesothelioma cancer patients can live for several years on average.<\/li>\n<li><strong>Symptom relief:<\/strong> PIPAC allows doctors to drain <a href=\"\/mesothelioma\/peritoneal\/effusion\/\">peritoneal effusions (ascites)<\/a> caused by painful fluid buildup in the abdominal cavity.<\/li>\n<\/ul>\n<p>If you\u2019re curious if PIPAC could help you, speak with your mesothelioma doctor to find out whether it can be added to your treatment plan.<\/p>\n<blockquote><p>\u201cI do think that PIPAC will become more and more prevalent in the future.\u201d<br \/>\n<strong>\u2013 Dr. Byrne Lee, peritoneal mesothelioma specialist at Stanford Medicine<\/strong><\/p><\/blockquote>\n<h2>Who Is Eligible for PIPAC Chemotherapy?<\/h2>\n<p>PIPAC is only available to patients who\u2019ve been diagnosed with peritoneal mesothelioma and other gastrointestinal cancers.<\/p>\n<p>PIPAC for mesothelioma may help patients:<\/p>\n<ul>\n<li><strong>As part of a comprehensive treatment plan:<\/strong> A study in <em>BMC Cancer<\/em> noted that PIPAC could be used before or during cytoreductive surgery or along systemic chemotherapy to help patients live longer.<\/li>\n<li><strong>With advanced disease:<\/strong> PIPAC can safely treat patients with late-stage peritoneal malignancies (cancers) since it has a low risk of toxicity or severe complications.<\/li>\n<li><strong>With limited treatment options:<\/strong> For patients who can\u2019t undergo major surgery, PIPAC offers a potential alternative to help them live longer.<\/li>\n<\/ul>\n<p>Need help accessing PIPAC? Use our <strong>Free Doctor Match<\/strong> to connect with specialists who can see if you\u2019re eligible to get PIPAC for mesothelioma and other top treatments.<\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>PIPAC Side Effects<\/h2>\n<p>While PIPAC for mesothelioma is less invasive than many other treatments, it can still cause some side effects.<\/p>\n<p><strong>Common side effects of PIPAC for mesothelioma include:<\/strong><\/p>\n<\/p>\n<ul class='columns-2'>\n<li>Bowel injury at surgery site<\/li>\n<li>Fever<\/li>\n<li>General discomfort<\/li>\n<li>Infection<\/li>\n<li>Mild stomach pain<\/li>\n<li>Nausea<\/li>\n<\/ul>\n<p>\n<p>People with certain pre-existing conditions may also be at higher risk for adverse events and severe side effects from PIPAC treatment. Your doctor will weigh the benefits and possible risks before recommending PIPAC for mesothelioma.<\/p>\n<h2>PIPAC and Mesothelioma Prognosis<\/h2>\n<p>PIPAC can potentially improve the <a href=\"\/mesothelioma\/prognosis\/\">mesothelioma prognosis<\/a> (expected health outlook) of patients since it helps destroy cancer tumors throughout the abdominal cavity.<\/p>\n<p>PIPAC for mesothelioma stopped tumors from spreading for 7.4 months on average in a 2021 study published in <em>The Annals of Surgical Oncology<\/em>.<\/p>\n<p>The overall survival time was <strong>33.5 months<\/strong> for patients who underwent PIPAC and cytoreduction with HIPEC. The cancer stopped spreading or shrank for <strong>nearly 3 years on average<\/strong> with this combination.<\/p>\n<p>In a <em>BMC Cancer<\/em> study, PIPAC helped stop the spread of peritoneal mesothelioma in more than 50% of patients. Also, 20% of patients went into complete <a href=\"\/mesothelioma\/prognosis\/remission-recurrence\/\">mesothelioma remission<\/a> (meaning all signs of cancer disappeared).<\/p>\n<h2>How Much Does PIPAC for Mesothelioma Cost?<\/h2>\n<p>PIPAC for mesothelioma is currently only available in clinical trials, which cost patients nothing to join.<\/p>\n<p>That said, the costs of other mesothelioma treatments and medical bills <strong>can exceed $400,000 each year.<\/strong><\/p>\n<p>This estimate doesn&#8217;t factor in other costs like lost wages or travel expenses if you don&#8217;t live close to the nearest treatment center.<\/p>\n<div class=\"callout-shortcode\"><style type=\"text\/css\">.callout-shortcode{background:#EDF8F9;border-radius:0 10px 10px 0;padding:20px 20px 20px 24px;margin:40px 0;max-width:860px;position:relative}.callout-shortcode:before{content:\" \";position:absolute;top:0;bottom:0;width:4px;height:100%;left:0;background:linear-gradient(180deg, #0FAEBF 0%, #EDF8F9 100%)}.callout-shortcode .callout-shortcode-heading{color:#100134;font-size:22px;display:block;margin:0 0 15px}.callout-shortcode:first-child{margin-top:0}.callout-shortcode:last-child{margin-bottom:0}.callout-shortcode .img-wrap{margin-bottom:20px}.callout-shortcode.hope>strong{padding-top:17px;padding-bottom:15px;padding-left:74px}.callout-shortcode.hope .img-wrap{left:22px;position:absolute;top:20px;width:59px}.callout-shortcode.hope .img-wrap:before{background:#fff url(\/wp-content\/uploads\/2024\/02\/mh-icon-65.png);background-position:center;background-repeat:no-repeat;background-size:70%;border-radius:30px;bottom:-10px;content:\"\";display:block;height:30px;position:absolute;right:-10px;width:30px}@media screen and (min-width: 768px){.callout-shortcode{padding:25px 25px 25px 34px}.callout-shortcode .callout-shortcode-heading{font-size:24px}.callout-shortcode .img-wrap{margin-bottom:0}.callout-shortcode.has-img{min-height:170px;padding-left:175px}.callout-shortcode.has-img .img-wrap{position:absolute;left:29px;top:25px;width:119px}.callout-shortcode.hope.has-img{padding-left:170px}.callout-shortcode.hope>strong{padding:0}.callout-shortcode.hope .img-wrap{width:109px}.callout-shortcode.hope .img-wrap:before{background-size:66%;bottom:-15px;height:42px;width:42px}}<\/style><div class=\"content\"><p>If you or a loved one is facing peritoneal mesothelioma, you may qualify for financial compensation to help pay for your treatment sessions. Call <strong><a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a><\/strong> to learn more.<\/p>\n<\/div><\/div>\n<h2>Mesothelioma PIPAC Clinical Trials<\/h2>\n<p>Doctors continue to study PIPAC for mesothelioma in <a href=\"\/treatment\/clinical-trials\/\">clinical trials<\/a>.<\/p>\n<p><strong>Ongoing PIPAC trials include:<\/strong><\/p>\n<ul>\n<li><strong>MESOTIP:<\/strong> Doctors are studying whether PIPAC and systemic chemotherapy are more effective for peritoneal mesothelioma compared to standard chemotherapy drugs (<a href=\"\/treatment\/chemotherapy\/drugs\/cisplatin\/\">cisplatin<\/a> and pemetrexed). This phase II trial is recruiting patients, with results expected in 2028.<\/li>\n<li><strong>Nab-PIPAC:<\/strong> PIPAC is combined with nanoparticle albumin-based paclitaxel for unresectable peritoneal metastases. Early results have shown promise in treating cancer and improving quality of life.<\/li>\n<li><strong>PIPAC-OPC7:<\/strong> Doctors are using PET\/CT <a href=\"\/mesothelioma\/diagnosis\/imaging-scans\/\">imaging scans<\/a> to monitor how effective PIPAC is in treating peritoneal cancers. Results are expected by the end of 2025.<\/li>\n<\/ul>\n<p>These studies are helping to establish PIPAC for mesothelioma as a safe and effective treatment option.<\/p>\n<h2>See if PIPAC for Mesothelioma Could Work for You<\/h2>\n<p>Recent studies have shown that PIPAC safely delivers chemotherapy to destroy peritoneal mesothelioma tumors, giving patients more time to make memories with loved ones.<\/p>\n<p>If you or a loved one is facing peritoneal mesothelioma, reach out to our team right now.<\/p>\n<p><strong>We can help you:<\/strong><\/p>\n<ul>\n<li>Learn more about PIPAC for mesothelioma and other treatments<\/li>\n<li>Connect with top mesothelioma specialists near you<\/li>\n<li>Pursue financial compensation to cover your medical expenses<\/li>\n<li>Secure the support you need to navigate life with mesothelioma<\/li>\n<\/ul>\n<p>Call <a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a> or use our <a href=\"\/get-matched\/\">Free Doctor Match<\/a> to get started.<\/p>\n<div class=\"faq-wrap\"><h2 class=\"faq-wrap-heading\">PIPAC for Mesothelioma FAQs<\/h2><div class=\"faq\" data-faq=\"1\"><h3 class=\"faq-heading\">What is the PIPAC procedure?<\/h3><div><p>Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment for abdominal cancers. It delivers chemotherapy as a pressurized aerosol into the abdominal cavity to help destroy tumors.<\/p>\n<p><strong>It can help treat:<\/strong><\/p>\n<ul>\n<li>Peritoneal mesothelioma<\/li>\n<li>Colorectal cancer<\/li>\n<li>Gastric cancer<\/li>\n<li><a href=\"\/cancer\/ovarian-cancer\/\">Ovarian cancer<\/a><\/li>\n<li>Peritoneal carcinomatosis<\/li>\n<li>Other peritoneal cancers<\/li>\n<\/ul>\n<p>Peritoneal aerosol chemotherapy penetrates deep into cancer tumors and shrinks them. This makes it more effective than systemic chemotherapy.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"2\"><h3 class=\"faq-heading\">Who is a candidate for PIPAC?<\/h3><div><p>Peritoneal mesothelioma patients are candidates for PIPAC as this treatment specifically targets the abdominal cavity.<\/p>\n<p>Doctors will assess a patient\u2019s overall health and cancer spread to determine if they will be a good candidate to receive PIPAC for mesothelioma.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"3\"><h3 class=\"faq-heading\">Is PIPAC better than HIPEC for mesothelioma?<\/h3><div><p>PIPAC may be better than hyperthermic intraperitoneal chemotherapy (HIPEC) if a patient has an advanced cancer like mesothelioma. Cytoreduction with HIPEC is a major procedure, so surgical oncology teams may not use it if the cancer is too widespread.<\/p>\n<p>In some cases, PIPAC may be a first-line (initial) treatment used to shrink tumors so patients can then undergo cytoreduction with HIPEC.<\/p>\n<p>If you or a loved one has been diagnosed with mesothelioma, consult with a doctor to learn if PIPAC is the right choice for your treatment plan.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"4\"><h3 class=\"faq-heading\">What is the survival rate of PIPAC for mesothelioma?<\/h3><div><p>Peritoneal mesothelioma patients who underwent PIPAC and cytoreduction with HIPEC had a <strong>2-year <a href=\"\/mesothelioma\/prognosis\/survival-rate\/\">survival rate<\/a> of 83.3%<\/strong> in a study from <em>The Annals of Surgical Oncology<\/em>.<\/p>\n<p>This shows that PIPAC for mesothelioma has the potential to help many patients live longer, especially when combined with other treatments.<\/p>\n<p><a href=\"\/about\/contact\/\">Contact our team now<\/a> for help accessing PIPAC for mesothelioma and other therapies to improve your life expectancy.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"5\"><h3 class=\"faq-heading\">What is the life expectancy of a patient undergoing PIPAC for mesothelioma?<\/h3><div><p>When PIPAC and cytoreduction with HIPEC were used together, peritoneal mesothelioma patients lived <strong>33.5 months<\/strong> on average, according to a 2021 study from <em>The Annals of Surgical Oncology<\/em>.<\/p>\n<p>Doctors can use PIPAC and other treatments to increase your <a href=\"\/mesothelioma\/prognosis\/life-expectancy\/peritoneal\/\">peritoneal mesothelioma life expectancy<\/a>. Which treatments will be used depends on the nature of your case.<\/p>\n<\/div><\/div><script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\",\"@type\": \"FAQPage\",\"mainEntity\": [{\"@type\": \"Question\",\"name\": \"What is the PIPAC procedure?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment for abdominal cancers. It delivers chemotherapy as a pressurized aerosol into the abdominal cavity to help destroy tumors.&lt;\/p&gt;\n&lt;p&gt;&lt;strong&gt;It can help treat:&lt;\/strong&gt;&lt;\/p&gt;\n&lt;ul&gt;\n&lt;li&gt;Peritoneal mesothelioma&lt;\/li&gt;\n&lt;li&gt;Colorectal cancer&lt;\/li&gt;\n&lt;li&gt;Gastric cancer&lt;\/li&gt;\n&lt;li&gt;Ovarian cancer&lt;\/li&gt;\n&lt;li&gt;Peritoneal carcinomatosis&lt;\/li&gt;\n&lt;li&gt;Other peritoneal cancers&lt;\/li&gt;\n&lt;\/ul&gt;\n&lt;p&gt;Peritoneal aerosol chemotherapy penetrates deep into cancer tumors and shrinks them. This makes it more effective than systemic chemotherapy.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Who is a candidate for PIPAC?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Peritoneal mesothelioma patients are candidates for PIPAC as this treatment specifically targets the abdominal cavity.&lt;\/p&gt;\n&lt;p&gt;Doctors will assess a patient\u2019s overall health and cancer spread to determine if they will be a good candidate to receive PIPAC for mesothelioma.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Is PIPAC better than HIPEC for mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;PIPAC may be better than hyperthermic intraperitoneal chemotherapy (HIPEC) if a patient has an advanced cancer like mesothelioma. Cytoreduction with HIPEC is a major procedure, so surgical oncology teams may not use it if the cancer is too widespread.&lt;\/p&gt;\n&lt;p&gt;In some cases, PIPAC may be a first-line (initial) treatment used to shrink tumors so patients can then undergo cytoreduction with HIPEC.&lt;\/p&gt;\n&lt;p&gt;If you or a loved one has been diagnosed with mesothelioma, consult with a doctor to learn if PIPAC is the right choice for your treatment plan.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"What is the survival rate of PIPAC for mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Peritoneal mesothelioma patients who underwent PIPAC and cytoreduction with HIPEC had a &lt;strong&gt;2-year survival rate of 83.3%&lt;\/strong&gt; in a study from &lt;em&gt;The Annals of Surgical Oncology&lt;\/em&gt;.&lt;\/p&gt;\n&lt;p&gt;This shows that PIPAC for mesothelioma has the potential to help many patients live longer, especially when combined with other treatments.&lt;\/p&gt;\n&lt;p&gt;Contact our team now for help accessing PIPAC for mesothelioma and other therapies to improve your life expectancy.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"What is the life expectancy of a patient undergoing PIPAC for mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;When PIPAC and cytoreduction with HIPEC were used together, peritoneal mesothelioma patients lived &lt;strong&gt;33.5 months&lt;\/strong&gt; on average, according to a 2021 study from &lt;em&gt;The Annals of Surgical Oncology&lt;\/em&gt;.&lt;\/p&gt;\n&lt;p&gt;Doctors can use PIPAC and other treatments to increase your peritoneal mesothelioma life expectancy. Which treatments will be used depends on the nature of your case.&lt;\/p&gt;\n\"}}]}<\/script><style type=\"text\/css\">.faq-wrap{background:#E4F4F6;padding:20px 15px;margin:40px -15px}.faq-wrap:first-child{margin-top:0}.faq-wrap:last-child{margin-bottom:0}.faq-wrap .faq{background:#fff;padding:15px;border-radius:10px;box-shadow:0px 20px 20px rgba(0,0,0,0.03);margin:15px 0 0 0}.faq-wrap .faq:first-child{margin-top:0}.faq-wrap .faq .faq-heading{color:#100134;font-size:21px;margin-bottom:15px}.faq-wrap .faq p{margin-bottom:20px;line-height:1.5}.faq-wrap .faq p:last-child{margin-bottom:0}.faq-wrap .faq .learn-more{color:#248AFF;display:block;padding-right:17px;text-align:right;position:relative;line-height:1}.faq-wrap .faq .learn-more:visited{color:#248AFF}.faq-wrap .faq .learn-more:visited:hover,.faq-wrap .faq .learn-more:hover{color:#34d}.faq-wrap .faq .learn-more:after{font-family:\"mesohope\" !important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e905\";position:absolute;right:0;top:3px}h2.faq-wrap-heading{margin-bottom:25px}@media screen and (min-width: 768px){.faq-wrap{padding:25px 15px}}@media screen and (min-width: 1024px){.faq-wrap{border-radius:10px;margin-left:auto;margin-right:auto;padding:25px}.faq-wrap .faq{padding:25px}.faq-heading{font-size:24px}}<\/style><\/div>\n","protected":false},"excerpt":{"rendered":"<p>What Is PIPAC for Mesothelioma? PIPAC is an innovative approach for treating malignant peritoneal mesothelioma. It involves turning chemotherapy into a high-pressure aerosol mist and delivering it directly into the abdominal cavity (peritoneum), which helps cancer-fighting drugs better penetrate tumor tissue. PIPAC for mesothelioma is currently only available in clinical trials, where it\u2019s showing promise&hellip;<\/p>\n","protected":false},"author":49,"featured_media":26412,"parent":128,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-26076","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/26076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/comments?post=26076"}],"version-history":[{"count":0,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/26076\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/128"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media\/26412"}],"wp:attachment":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media?parent=26076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}