{"id":29806,"date":"2025-12-15T14:48:06","date_gmt":"2025-12-15T19:48:06","guid":{"rendered":"https:\/\/www.mesotheliomahope.com\/?page_id=29806"},"modified":"2025-12-17T15:41:42","modified_gmt":"2025-12-17T20:41:42","slug":"mesomark","status":"publish","type":"page","link":"https:\/\/www.mesotheliomahope.com\/mesothelioma\/diagnosis\/biomarkers-blood-tests\/mesomark\/","title":{"rendered":"MESOMARK\u00ae Blood Test for Mesothelioma"},"content":{"rendered":"<h2>What Is the MESOMARK Blood Test?<\/h2>\n<p>The MESOMARK blood test measures the amount of a protein called mesothelin in your bloodstream. Mesothelin is normally present in very small amounts, but <a href=\"\/mesothelioma\/\">mesothelioma<\/a> cells can release more of it as they grow. Because of this, doctors sometimes use the test to get a better sense of how active the disease may be.<\/p>\n<p>The test isn\u2019t used to confirm mesothelioma, as <strong>that can only be done with a biopsy<\/strong>. Instead, this <a href=\"\/mesothelioma\/diagnosis\/biomarkers-blood-tests\/\">blood test<\/a> provides supporting information that can help your medical team understand your baseline before treatment starts. Your doctor may use it to see whether your mesothelin protein level is higher than expected and then compare future tests to this starting point.<\/p>\n<div class=\"blockquote-w-image \"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/03\/liz-logan-zoom-flip.jpg\" alt=\"\" \/><blockquote><p>&#8220;A mesothelin test can be helpful, but it\u2019s not required to make a <a href=\"\/mesothelioma\/diagnosis\/\">mesothelioma diagnosis<\/a>. Doctors choose whether to order it based on your symptoms, your asbestos exposure history, and what they already see on your imaging scans.&#8221;<\/p>\n<footer>&ndash;<cite> Liz Logan, Mesothelioma Hope\u2019s Oncology Nurse Navigator<\/cite><\/footer><\/blockquote><style type=\"text\/css\">.blockquote-w-image{position:relative;margin:40px auto}.blockquote-w-image blockquote{background:none;border-left:none;padding:25px;margin-top:0;padding-bottom:0;font-size:inherit;line-height:inherit}.blockquote-w-image blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote p{margin-bottom:0}.blockquote-w-image img{width:100px;border:none;border-radius:100%;box-shadow:none;position:relative;margin:0 auto}.blockquote-w-image.alternative{margin:60px auto}.blockquote-w-image.alternative blockquote{padding:25px 25px 25px 80px;padding-bottom:25px;background-color:#E4F4F6}.blockquote-w-image.alternative img{position:absolute;left:20px;top:25px;z-index:1;width:50px;border:1px solid #fff;box-shadow:0 0 10px rgba(34,34,34,0.2);border-radius:100%}.blockquote-w-image.with-border{background:none;border-left:4px solid #0FAEBF}.blockquote-w-image.with-border blockquote{background:none;border-radius:0;padding:10px 25px}.blockquote-w-image.with-border blockquote footer cite{font-size:inherit}.blockquote-w-image blockquote:before{display:none}@media screen and (min-width: 769px){.blockquote-w-image img{position:absolute;left:0;top:0}.blockquote-w-image blockquote{padding:0 25px 0 125px;min-height:90px}}@media screen and (min-width: 1024px){.blockquote-w-image.alternative blockquote{padding-left:105px}.blockquote-w-image.alternative blockquote footer cite{font-size:16px}.entry-content .blockquote-w-image.alternative img{width:60px;left:25px}}<\/style><\/div>\n<p><strong>Not all mesothelioma patients have elevated mesothelin levels.<\/strong> A normal result doesn\u2019t mean the cancer is gone or in remission. It simply means this particular substance isn\u2019t as useful for tracking your case. If your levels are higher, your care team may check them periodically to monitor how well treatment is working or to watch for changes that may need attention.<\/p>\n<h3>Key Facts About the Mesothelin Test<\/h3>\n<ul>\n<li>First approved blood test designed to help doctors diagnose mesothelioma<\/li>\n<li>Not a standalone diagnostic test, since <strong>only a <\/strong><a href=\"\/mesothelioma\/diagnosis\/biopsy\/\"><strong>biopsy<\/strong><\/a><strong> can confirm cancer<\/strong><\/li>\n<li>Often ordered with imaging tests such as CT scans, MRIs, and X-rays<\/li>\n<li>Useful for tracking the body\u2019s response to mesothelioma treatment<\/li>\n<\/ul>\n<p>Get our <strong>Free Mesothelioma Guide<\/strong> shipped overnight to learn more about the tests used to diagnose this cancer and the latest treatment options available.<\/p>\n<div data-vqueid=\"1361\" class=\"widget widget_oscar-vque default image-right has-img\"><style type=\"text\/css\" data-style=\"default\">.widget_oscar-vque.default{margin:60px auto;max-width:315px}.widget_oscar-vque.default:first-child{margin-top:0}.widget_oscar-vque.default:last-child{margin-bottom:0}.widget_oscar-vque.default>a{background:#2F293D;display:block;padding:20px;border-radius:10px;color:#fff;text-decoration:none}.widget_oscar-vque.default img{margin:0 auto 20px;max-width:150px;width:100%}.widget_oscar-vque.default .vque-content{font-size:16px;text-align:center}.widget_oscar-vque.default strong.subheading{display:block;line-height:1;font-size:14px;margin-bottom:5px}.widget_oscar-vque.default strong.heading{font-size:20px;display:block;margin:0 0 25px}.widget_oscar-vque.default ul{font-size:16px;text-align:left;list-style:none;max-width:265px;line-height:1.4;margin:15px auto 25px}.widget_oscar-vque.default ul li{padding-left:28px;margin-bottom:10px}.widget_oscar-vque.default ul li:last-child{margin-bottom:0}.widget_oscar-vque.default ul li:before{font-family:\"mesohope\" !important;font-display:swap;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e904\";border:none;position:absolute;left:0;top:0;background:#0FAEBF;width:20px;height:20px;border-radius:20px;line-height:20px;text-align:center;font-size:12px}.widget_oscar-vque.default strong.button.arrow{width:100%}@media screen and (min-width: 768px){.widget_oscar-vque.default{max-width:620px}.widget_oscar-vque.default>a{padding:0}.widget_oscar-vque.default>a>div{display:block;display:flex;align-items:center;flex-wrap:wrap;flex-direction:row-reverse}.widget_oscar-vque.default>a>div>div{padding:0 25px 0 0;width:41%}.widget_oscar-vque.default>a .vque-content{width:59%;padding:30px;text-align:left}.widget_oscar-vque.default img{max-width:90%;margin-bottom:0}.widget_oscar-vque.default strong.subheading{font-size:16px}.widget_oscar-vque.default strong.heading{font-size:24px;margin:0 0 16px}.widget_oscar-vque.default ul{max-width:none}.widget_oscar-vque.default strong.button.arrow{width:auto}.widget_oscar-vque.default.image-left>a>div{display:block;position:relative;overflow:hidden}.widget_oscar-vque.default.image-left>a>div img{max-width:100%}.widget_oscar-vque.default.image-left>a>div>div{float:left}.widget_oscar-vque.default.image-left>a>div>div:first-child{width:27%;padding:30px}.widget_oscar-vque.default.image-left>a>div>div.vque-content{width:73%;padding-left:0}}<\/style><a href=\"\/mesothelioma-guide\/\" title=\"Get Your Free 2026 Mesothelioma Guide\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Your Free 2026 Mesothelioma Guide Ad\" data-desktop-image=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical.png\"><div><div><div class=\"image-fade\"><img loading=\"lazy\" decoding=\"async\" width=\"296\" height=\"290\" src=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical.png\" class=\"attachment-Medium size-Medium wp-post-image\" alt=\"Mesothelioma Guide Images\" srcset=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical.png 296w, https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical-55x55.png 55w, https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical-102x100.png 102w\" sizes=\"(max-width: 296px) 100vw, 296px\" \/><\/div><\/div><div class=\"vque-content\"><strong class=\"heading\">Get Your Free 2026 Mesothelioma Guide<\/strong><ul>\n<li>Symptoms &amp; staging<\/li>\n<li>Average prognosis<\/li>\n<li>Life-extending treatments<\/li>\n<\/ul>\n<p><strong class=\"button arrow\" title=\"Get Your Free Guide\">Get Your Free Guide<\/strong><\/p><\/div><\/div><\/a><\/div>\n<h2>What to Expect During the MESOMARK Test<\/h2>\n<p>The MESOMARK blood test is quick, simple, and similar to any routine blood draw. You typically do not need to fast or prepare in any special way beforehand.<\/p>\n<p><strong>Here\u2019s what typically happens during the test:<\/strong><\/p>\n<ol>\n<li><strong>Blood sample collection: <\/strong>A nurse or technician draws a small amount of blood from a vein in your arm.<\/li>\n<li><strong>Lab analysis using an ELISA test: <\/strong>The sample goes to a specialized lab, where an enzyme-linked immunosorbent assay (ELISA) test measures the level of soluble mesothelin-related peptides (SMRPs). These SMRPs are proteins shed by mesothelioma cells.<\/li>\n<li><strong>Results sent to your doctor: <\/strong>Your care team receives a report showing whether your mesothelin level is within the expected range or higher than average.<\/li>\n<li><strong>Review and follow-up recommendations: <\/strong>Higher mesothelin protein levels do not necessarily mean you have mesothelioma, but they may prompt more testing, such as a CT scan, MRI, or biopsy. Your doctor will explain how your results fit with your symptoms and medical history.<\/li>\n<\/ol>\n<p>The MESOMARK assay (analysis) is only one of many tests used to help diagnose mesothelioma. If your mesothelin level is higher than expected, your doctor may recommend additional testing to better understand the cause.<\/p>\n<p>If your follow-up imaging or biopsy confirms you have mesothelioma, your doctor will work with you to develop a personalized <a href=\"\/treatment\/\">treatment plan<\/a> based on your cell type, cancer stage, overall health, and other important factors.<\/p>\n<h2>Who Should Get a Mesothelin Test?<\/h2>\n<p>A mesothelin cancer test is recommended for people who may have a higher risk of developing mesothelioma. This includes those who have been exposed to asbestos or who are experiencing symptoms that affect the chest or abdomen, where mesothelioma most commonly forms.<\/p>\n<p><strong>Candidates for the MESOMARK blood test include: <\/strong><\/p>\n<ul>\n<li>Anyone living near industrial work sites, factories, or mines<\/li>\n<li>Families of workers who may have been <a href=\"\/asbestos\/exposure\/secondary\/\">exposed to asbestos secondhand<\/a><\/li>\n<li>Patients with imaging scans that raise concern for cancer<\/li>\n<li>People with known <a href=\"\/asbestos\/exposure\/\">asbestos exposure<\/a>, even if it was short-term<\/li>\n<li>Those with unexplained symptoms like chest pain, breathing issues, or bloating<\/li>\n<\/ul>\n<p>If you fall into one of these groups, your doctor may order an SMRP test to gather more information before recommending next steps. Depending on the results, your care team may suggest further testing, such as a CT scan or <a href=\"\/mesothelioma\/diagnosis\/biopsy\/thoracoscopy\/\">video-assisted thoracoscopic surgery (VATS)<\/a> to collect tissue samples for biopsy.<\/p>\n<h2>How Accurate Is the Mesothelin Test for Mesothelioma?<\/h2>\n<p>The mesothelin test is more accurate in diagnosing some types of mesothelioma than others. For example, it is most effective at diagnosing <a href=\"\/mesothelioma\/cell-types\/epithelioid\/\">epithelioid mesothelioma<\/a>, the most common cell type of this cancer. It is less sensitive to <a href=\"\/mesothelioma\/cell-types\/sarcomatoid\/\">sarcomatoid tumors<\/a>.<\/p>\n<p>Studies published in peer-reviewed research journals show that SMRP has moderate sensitivity but strong specificity. This means higher SMRP levels are more likely to be tied to mesothelioma cases than to other diseases.<\/p>\n<p><strong>Many researchers also test additional serum biomarkers like:<\/strong><\/p>\n<ul>\n<li>Fibulin-3<\/li>\n<li>N-ERC (megakaryocyte potentiating factor \/ MPF)<\/li>\n<li>Osteopontin<\/li>\n<\/ul>\n<p>These biomarkers are being explored in <a href=\"\/treatment\/clinical-trials\/\">clinical trials<\/a> to see whether combining them with SMRP can improve early detection and prognostic predictions.<\/p>\n<p>Use our <strong>Free Doctor Match service<\/strong> to get help finding a specialist who understands mesothelioma and all available testing options.<\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2>Can the Mesothelin Test Detect Mesothelioma Early?<\/h2>\n<p><a href=\"\/mesothelioma\/diagnosis\/screening\/\">Early detection<\/a> is vital for mesothelioma patients, as identifying the cancer before it spreads can significantly improve treatment outcomes and life expectancy. Because of this, researchers are actively investigating whether mesothelin testing can help catch the disease sooner.<\/p>\n<p><strong>Current research into this diagnostic tool shows:<\/strong><\/p>\n<ul>\n<li>Combining mesothelin testing with other serum biomarkers may improve the chances of early detection.<\/li>\n<li>In some cases, SMRP levels may rise years before mesothelioma tumors actually develop.<\/li>\n<li>Not all mesothelioma patients have high mesothelin levels, particularly in the earliest stages of the disease.<\/li>\n<li>The test is more useful for monitoring those with known asbestos exposure than for screening the general population.<\/li>\n<\/ul>\n<p>Mesothelin testing may help doctors monitor people at high risk, but it cannot detect mesothelioma early or replace other medical tests.<\/p>\n<h2>How Mesothelin Blood Tests Help After Diagnosis<\/h2>\n<p>For patients already living with mesothelioma, the mesothelioma protein test can be a helpful part of ongoing treatment planning. Many cancer specialists analyze this information along with imaging scans and patient-reported symptoms to guide their medical decisions.<\/p>\n<p><strong>Doctors may use MESOMARK testing to:<\/strong><\/p>\n<ul>\n<li>Assess response to chemotherapy or <a href=\"\/treatment\/immunotherapy\/\">immunotherapy<\/a><\/li>\n<li>Compare blood test results with scans and symptoms<\/li>\n<li>Confirm whether the current treatment is effective<\/li>\n<li>Look for signs that the cancer may be growing or returning<strong><br \/>\n<\/strong><\/li>\n<\/ul>\n<p>Your medical team will determine whether your SMRP levels are rising, stable, or falling at various points throughout your treatment. The results help them decide if they need to change a dose, add a new medication, or switch approaches entirely.<\/p>\n<h2>Hope for Mesothelioma Patients: Get the Right Diagnosis<\/h2>\n<p>The MESOMARK blood test can be an important way to help diagnose mesothelioma early and guide you toward the right care. If you or a loved one has a history of asbestos exposure or symptoms of mesothelioma, you\u2019re not alone.<\/p>\n<p><strong>Our nurses and Patient Advocates can help you:<\/strong><\/p>\n<ul>\n<li>Find top cancer center specialists<\/li>\n<li>Understand diagnostic testing options<\/li>\n<li>Access clinical trials and treatment programs<\/li>\n<li>Pursue compensation to cover medical costs<\/li>\n<li>Get support without feeling overwhelmed<\/li>\n<\/ul>\n<p>Give us a call at <strong><a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a> <\/strong>or get our <a href=\"\/mesothelioma-guide\/\">Free Mesothelioma Guide<\/a> shipped overnight to learn more about how we can help your family.<\/p>\n<div class=\"faq-wrap\"><h2 class=\"faq-wrap-heading\">Mesothelin Blood Test FAQs<\/h2><div class=\"faq\" data-faq=\"1\"><h3 class=\"faq-heading\">Will a blood test show mesothelioma?<\/h3><div><p>A blood test cannot confirm whether someone has mesothelioma, but <strong>it can provide helpful clues<\/strong>. Mesothelin and other proteins may increase when mesothelioma is developing.<\/p>\n<p>If a blood test shows higher-than-normal levels, your doctor may look more closely with <a href=\"\/mesothelioma\/diagnosis\/imaging-scans\/\">imaging scans<\/a> or other tests. Think of it as an early signal that something may need more investigation, <strong>not a final answer on its own<\/strong>.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"2\"><h3 class=\"faq-heading\">What cancers are mesothelin-positive?<\/h3><div><p>Mesothelin is most commonly elevated in mesothelioma, especially the type that forms around the lungs (<a href=\"\/mesothelioma\/pleural\/\">pleural mesothelioma<\/a>). However, other cancers can sometimes produce higher mesothelin levels as well.<\/p>\n<p><strong>These include:<\/strong><\/p>\n<ul>\n<li><a href=\"\/cancer\/ovarian-cancer\/\">Ovarian cancer<\/a><\/li>\n<li>Pancreatic cancer<\/li>\n<li>Some <a href=\"\/cancer\/lung-cancer\/\">lung cancers<\/a><\/li>\n<\/ul>\n<p>Because mesothelin can rise for several reasons, doctors use this result as one part of the bigger diagnostic picture, not as proof of a specific cancer.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"3\"><h3 class=\"faq-heading\">Does mesothelioma show up in bloodwork?<\/h3><div><p>Mesothelioma<strong> does<\/strong> <strong>not<\/strong> show up directly in bloodwork the way some conditions do. Instead, doctors may see changes in mesothelin and other biomarkers that suggest more testing is needed.<\/p>\n<p>Some people with mesothelioma have elevated mesothelin levels, while others never do. For this reason, a blood test can support the diagnostic process but cannot confirm or rule out mesothelioma by itself. Imaging scans and a biopsy are still essential for an accurate diagnosis.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"4\"><h3 class=\"faq-heading\">Can the MESOMARK blood test diagnose mesothelioma?<\/h3><div><p><strong>No<\/strong>, the MESOMARK blood test cannot diagnose mesothelioma on its own. Instead, it helps doctors identify whether more testing, such as a biopsy or CT scan, is needed.<\/p>\n<p>High levels of SMRP found through a MESOMARK test could mean you have mesothelioma, especially if you have a history of asbestos exposure, but they don\u2019t confirm cancer. Only a biopsy can provide a definitive diagnosis of mesothelioma.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"5\"><h3 class=\"faq-heading\">Why do mesothelin levels become elevated?<\/h3><div><p>Mesothelin levels rise when mesothelioma cells shed proteins into the bloodstream. This happens most often in malignant pleural mesothelioma and especially in the epithelioid cell type.<\/p>\n<p>However, elevated mesothelin does not always indicate mesothelioma. Some other cancers and inflammatory conditions can also increase mesothelin. Doctors interpret the results alongside imaging scans and asbestos exposure history.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"6\"><h3 class=\"faq-heading\">What happens if my mesothelin results are high?<\/h3><div><p>If your mesothelin levels are elevated, your doctor will likely order more tests. Common next steps include a CT scan, X-ray, or MRI to look for tumors or abnormalities.<\/p>\n<p>If your imaging scans raise concern, a biopsy will be ordered to confirm a diagnosis. Elevated levels may also prompt referral to a mesothelioma specialist for further evaluation.<\/p>\n<p>If you need help finding a mesothelioma specialist, <strong>our team can connect you with top doctors<\/strong> who diagnose this disease every day. <a href=\"\/get-matched\/\">Use our Free Doctor Match service to get started<\/a>.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"7\"><h3 class=\"faq-heading\">What lab does the MESOMARK blood test?<\/h3><div><p>The MESOMARK blood test is made by Fujirebio Diagnostics, but it\u2019s not performed in a single location. Instead, the blood sample your doctor collects is sent to a laboratory that has the equipment needed to run this type of test.<\/p>\n<p>These labs use a method called enzyme-linked immunosorbent assay (ELISA) to measure mesothelin levels, which helps your care team understand whether further testing may be needed.<\/p>\n<p><strong>You don\u2019t have to find one of these labs on your own.<\/strong> Your doctor or <a href=\"\/cancer-centers\/\">cancer center<\/a> will handle the process of sending your sample to a qualified lab. Once the test is complete, the results are sent back to your care team so they can walk you through what the numbers mean and how they fit into your overall diagnosis and treatment plan.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"8\"><h3 class=\"faq-heading\">Do insurance plans cover MESOMARK testing?<\/h3><div><p>Most insurance plans cover diagnostic testing recommended by your doctor, including mesothelin blood tests like MESOMARK.<\/p>\n<p>However, coverage varies depending on your insurer, policy, and deductible. If you are concerned about paying for mesothelin testing, our Patient Advocates can help you explore <a href=\"\/resources\/financial\/\">resources for financial assistance<\/a>.<\/p>\n<\/div><\/div><script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\",\"@type\": \"FAQPage\",\"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Will a blood test show mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;A blood test cannot confirm whether someone has mesothelioma, but &lt;strong&gt;it can provide helpful clues&lt;\/strong&gt;. Mesothelin and other proteins may increase when mesothelioma is developing.&lt;\/p&gt;\n&lt;p&gt;If a blood test shows higher-than-normal levels, your doctor may look more closely with imaging scans or other tests. Think of it as an early signal that something may need more investigation, &lt;strong&gt;not a final answer on its own&lt;\/strong&gt;.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"What cancers are mesothelin-positive?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Mesothelin is most commonly elevated in mesothelioma, especially the type that forms around the lungs (pleural mesothelioma). However, other cancers can sometimes produce higher mesothelin levels as well.&lt;\/p&gt;\n&lt;p&gt;&lt;strong&gt;These include:&lt;\/strong&gt;&lt;\/p&gt;\n&lt;ul&gt;\n&lt;li&gt;Ovarian cancer&lt;\/li&gt;\n&lt;li&gt;Pancreatic cancer&lt;\/li&gt;\n&lt;li&gt;Some lung cancers&lt;\/li&gt;\n&lt;\/ul&gt;\n&lt;p&gt;Because mesothelin can rise for several reasons, doctors use this result as one part of the bigger diagnostic picture, not as proof of a specific cancer.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Does mesothelioma show up in bloodwork?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Mesothelioma&lt;strong&gt; does&lt;\/strong&gt; &lt;strong&gt;not&lt;\/strong&gt; show up directly in bloodwork the way some conditions do. Instead, doctors may see changes in mesothelin and other biomarkers that suggest more testing is needed.&lt;\/p&gt;\n&lt;p&gt;Some people with mesothelioma have elevated mesothelin levels, while others never do. For this reason, a blood test can support the diagnostic process but cannot confirm or rule out mesothelioma by itself. Imaging scans and a biopsy are still essential for an accurate diagnosis.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Can the MESOMARK blood test diagnose mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;&lt;strong&gt;No&lt;\/strong&gt;, the MESOMARK blood test cannot diagnose mesothelioma on its own. Instead, it helps doctors identify whether more testing, such as a biopsy or CT scan, is needed.&lt;\/p&gt;\n&lt;p&gt;High levels of SMRP found through a MESOMARK test could mean you have mesothelioma, especially if you have a history of asbestos exposure, but they don\u2019t confirm cancer. Only a biopsy can provide a definitive diagnosis of mesothelioma.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Why do mesothelin levels become elevated?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Mesothelin levels rise when mesothelioma cells shed proteins into the bloodstream. This happens most often in malignant pleural mesothelioma and especially in the epithelioid cell type.&lt;\/p&gt;\n&lt;p&gt;However, elevated mesothelin does not always indicate mesothelioma. Some other cancers and inflammatory conditions can also increase mesothelin. Doctors interpret the results alongside imaging scans and asbestos exposure history.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"What happens if my mesothelin results are high?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;If your mesothelin levels are elevated, your doctor will likely order more tests. Common next steps include a CT scan, X-ray, or MRI to look for tumors or abnormalities.&lt;\/p&gt;\n&lt;p&gt;If your imaging scans raise concern, a biopsy will be ordered to confirm a diagnosis. Elevated levels may also prompt referral to a mesothelioma specialist for further evaluation.&lt;\/p&gt;\n&lt;p&gt;If you need help finding a mesothelioma specialist, &lt;strong&gt;our team can connect you with top doctors&lt;\/strong&gt; who diagnose this disease every day. Use our Free Doctor Match service to get started.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"What lab does the MESOMARK blood test?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;The MESOMARK blood test is made by Fujirebio Diagnostics, but it\u2019s not performed in a single location. Instead, the blood sample your doctor collects is sent to a laboratory that has the equipment needed to run this type of test.&lt;\/p&gt;\n&lt;p&gt;These labs use a method called enzyme-linked immunosorbent assay (ELISA) to measure mesothelin levels, which helps your care team understand whether further testing may be needed.&lt;\/p&gt;\n&lt;p&gt;&lt;strong&gt;You don\u2019t have to find one of these labs on your own.&lt;\/strong&gt; Your doctor or cancer center will handle the process of sending your sample to a qualified lab. Once the test is complete, the results are sent back to your care team so they can walk you through what the numbers mean and how they fit into your overall diagnosis and treatment plan.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Do insurance plans cover MESOMARK testing?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;Most insurance plans cover diagnostic testing recommended by your doctor, including mesothelin blood tests like MESOMARK.&lt;\/p&gt;\n&lt;p&gt;However, coverage varies depending on your insurer, policy, and deductible. If you are concerned about paying for mesothelin testing, our Patient Advocates can help you explore resources for financial assistance.&lt;\/p&gt;\n\"}}]}<\/script><style type=\"text\/css\">.faq-wrap{background:#E4F4F6;padding:20px 15px;margin:40px -15px}.faq-wrap:first-child{margin-top:0}.faq-wrap:last-child{margin-bottom:0}.faq-wrap .faq{background:#fff;padding:15px;border-radius:10px;box-shadow:0px 20px 20px rgba(0,0,0,0.03);margin:15px 0 0 0}.faq-wrap .faq:first-child{margin-top:0}.faq-wrap .faq .faq-heading{color:#100134;font-size:21px;margin-bottom:15px}.faq-wrap .faq p{margin-bottom:20px;line-height:1.5}.faq-wrap .faq p:last-child{margin-bottom:0}.faq-wrap .faq .learn-more{color:#248AFF;display:block;padding-right:17px;text-align:right;position:relative;line-height:1}.faq-wrap .faq .learn-more:visited{color:#248AFF}.faq-wrap .faq .learn-more:visited:hover,.faq-wrap .faq .learn-more:hover{color:#34d}.faq-wrap .faq .learn-more:after{font-family:\"mesohope\" !important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e905\";position:absolute;right:0;top:3px}h2.faq-wrap-heading{margin-bottom:25px}@media screen and (min-width: 768px){.faq-wrap{padding:25px 15px}}@media screen and (min-width: 1024px){.faq-wrap{border-radius:10px;margin-left:auto;margin-right:auto;padding:25px}.faq-wrap .faq{padding:25px}.faq-heading{font-size:24px}}<\/style><\/div>\n","protected":false},"excerpt":{"rendered":"<p>What Is the MESOMARK Blood Test? The MESOMARK blood test measures the amount of a protein called mesothelin in your bloodstream. Mesothelin is normally present in very small amounts, but mesothelioma cells can release more of it as they grow. Because of this, doctors sometimes use the test to get a better sense of how&hellip;<\/p>\n","protected":false},"author":49,"featured_media":0,"parent":22206,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-29806","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/29806","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/comments?post=29806"}],"version-history":[{"count":0,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/29806\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/22206"}],"wp:attachment":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media?parent=29806"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}