{"id":840,"date":"2020-04-17T13:28:40","date_gmt":"2020-04-17T17:28:40","guid":{"rendered":"https:\/\/www.mesotheliomahope.com\/?page_id=840"},"modified":"2023-10-05T17:36:29","modified_gmt":"2023-10-05T21:36:29","slug":"photodynamic-therapy","status":"publish","type":"page","link":"https:\/\/www.mesotheliomahope.com\/treatment\/photodynamic-therapy\/","title":{"rendered":"Photodynamic Therapy"},"content":{"rendered":"<h2>What Is Photodynamic Therapy?<\/h2>\n<p>Photodynamic therapy (PDT) is a promising new mesothelioma treatment still undergoing research in clinical trials. As a light-based treatment, photodynamic therapy works by aiming a special light directly at cancer cells treated with light-reactive drugs. This treatment kills mesothelioma cells while causing less damage to surrounding healthy cells.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-21082\" src=\"\/wp-content\/uploads\/2022\/12\/photodynamic-therapy-300x180.jpg\" alt=\"Photodynamic therapy\" width=\"300\" height=\"180\" srcset=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2022\/12\/photodynamic-therapy-300x180.jpg 300w, https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2022\/12\/photodynamic-therapy.jpg 762w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>Because <a href=\"\/mesothelioma\/\">mesothelioma<\/a> is one of the toughest cancers to treat, doctors may combine multiple, targeted treatments together in a specific order to build a tailored treatment plan that\u2019s unique to each patient. As a less invasive treatment method, photodynamic therapy is regarded as one of the best therapies to administer before or during surgery as part of a <a href=\"\/treatment\/multimodal-therapy\/\">multimodal treatment plan<\/a>.<\/p>\n<p>Photodynamic therapy plays a supporting role in the surgical removal of mesothelioma tumors and has been shown to improve survival rates.<\/p>\n<p class=\"p1\"><span class=\"s1\">Learn how photodynamic therapy and other treatments can help you in our <strong>Free Mesothelioma Guide<\/strong>.\u00a0<\/span><\/p>\n<div data-vqueid=\"1361\" class=\"widget widget_oscar-vque default image-right has-img\"><style type=\"text\/css\" data-style=\"default\">.widget_oscar-vque.default{margin:60px auto;max-width:315px}.widget_oscar-vque.default:first-child{margin-top:0}.widget_oscar-vque.default:last-child{margin-bottom:0}.widget_oscar-vque.default>a{background:#2F293D;display:block;padding:20px;border-radius:10px;color:#fff;text-decoration:none}.widget_oscar-vque.default img{margin:0 auto 20px;max-width:150px;width:100%}.widget_oscar-vque.default .vque-content{font-size:16px;text-align:center}.widget_oscar-vque.default strong.subheading{display:block;line-height:1;font-size:14px;margin-bottom:5px}.widget_oscar-vque.default strong.heading{font-size:20px;display:block;margin:0 0 25px}.widget_oscar-vque.default ul{font-size:16px;text-align:left;list-style:none;max-width:265px;line-height:1.4;margin:15px auto 25px}.widget_oscar-vque.default ul li{padding-left:28px;margin-bottom:10px}.widget_oscar-vque.default ul li:last-child{margin-bottom:0}.widget_oscar-vque.default ul li:before{font-family:\"mesohope\" !important;font-display:swap;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;content:\"\\e904\";border:none;position:absolute;left:0;top:0;background:#0FAEBF;width:20px;height:20px;border-radius:20px;line-height:20px;text-align:center;font-size:12px}.widget_oscar-vque.default strong.button.arrow{width:100%}@media screen and (min-width: 768px){.widget_oscar-vque.default{max-width:620px}.widget_oscar-vque.default>a{padding:0}.widget_oscar-vque.default>a>div{display:block;display:flex;align-items:center;flex-wrap:wrap;flex-direction:row-reverse}.widget_oscar-vque.default>a>div>div{padding:0 25px 0 0;width:41%}.widget_oscar-vque.default>a .vque-content{width:59%;padding:30px;text-align:left}.widget_oscar-vque.default img{max-width:90%;margin-bottom:0}.widget_oscar-vque.default strong.subheading{font-size:16px}.widget_oscar-vque.default strong.heading{font-size:24px;margin:0 0 16px}.widget_oscar-vque.default ul{max-width:none}.widget_oscar-vque.default strong.button.arrow{width:auto}.widget_oscar-vque.default.image-left>a>div{display:block;position:relative;overflow:hidden}.widget_oscar-vque.default.image-left>a>div img{max-width:100%}.widget_oscar-vque.default.image-left>a>div>div{float:left}.widget_oscar-vque.default.image-left>a>div>div:first-child{width:27%;padding:30px}.widget_oscar-vque.default.image-left>a>div>div.vque-content{width:73%;padding-left:0}}<\/style><a href=\"\/mesothelioma-guide\/\" title=\"Get Your Free 2026 Mesothelioma Guide\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Your Free 2026 Mesothelioma Guide Ad\" data-desktop-image=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical.png\"><div><div><div class=\"image-fade\"><img loading=\"lazy\" decoding=\"async\" width=\"296\" height=\"290\" src=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical.png\" class=\"attachment-Medium size-Medium wp-post-image\" alt=\"Mesothelioma Guide Images\" srcset=\"https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical.png 296w, https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical-55x55.png 55w, https:\/\/www.mesotheliomahope.com\/wp-content\/uploads\/2020\/07\/guide-image-vertical-102x100.png 102w\" sizes=\"(max-width: 296px) 100vw, 296px\" \/><\/div><\/div><div class=\"vque-content\"><strong class=\"heading\">Get Your Free 2026 Mesothelioma Guide<\/strong><ul>\n<li>Symptoms &amp; staging<\/li>\n<li>Average prognosis<\/li>\n<li>Life-extending treatments<\/li>\n<\/ul>\n<p><strong class=\"button arrow\" title=\"Get Your Free Guide\">Get Your Free Guide<\/strong><\/p><\/div><\/div><\/a><\/div>\n<h2 id=\"how-it-works\">How Does Photodynamic Therapy Work?<\/h2>\n<p>At a basic level, photodynamic therapy is an anticancer light treatment. PDT uses a laser light that activates a drug, targeting mesothelioma cells specifically so that healthy cells in the lung aren&#8217;t harmed.<\/p>\n<p><strong>The process for photodynamic therapy follows these steps:<\/strong><\/p>\n<ol class=\"special numbers\">\n<li>A photosensitizing solution is injected into the patient.<\/li>\n<li>Between 1-3 days, the solution is absorbed by the cancerous cells.<\/li>\n<li>During intraoperative photodynamic therapy, a light is applied, causing the photosensitizer to chemically react, killing the mesothelioma cells.<\/li>\n<li>Any visible tumors are removed in surgery, and the light is applied to kill any remaining mesothelioma cells.<\/li>\n<\/ol>\n<h2 id=\"benefits\">Benefits of Photodynamic Therapy for Mesothelioma<\/h2>\n<p>There are definite advantages to using photodynamic therapy for mesothelioma. It has few known side effects and is essential in prolonging the life of those diagnosed with mesothelioma.<\/p>\n<p><strong>Benefits of photodynamic therapy include:<\/strong><\/p>\n<ul class=\"special diamond\">\n<li>Acting as a cancer-centric treatment, meaning less damage to healthy cells<\/li>\n<li>Allowing repeated use on the tumor site with few side effects<\/li>\n<li>Causing no long-term side effects<\/li>\n<li>Ensuring uniform illumination of the chest cavity, making it easier to localize the mesothelioma<\/li>\n<li>Improving life expectancy up to several months, and in some cases, years<\/li>\n<li>Requiring fewer dosages than radiation<\/li>\n<\/ul>\n<h2>Current and Ongoing Research Into Photodynamic Therapy<\/h2>\n<p>Because of PDT&#8217;s encouraging survival results, the American Cancer Society has dedicated a lot of research to exploring this treatment. There are hundreds of clinical trials involving photodynamic therapy that have occurred over the past two decades.<\/p>\n<p>The current and ongoing research into photodynamic therapy has shown that it may be a viable mainstream <a href=\"\/treatment\/\">treatment for mesothelioma<\/a>.<\/p>\n<h3>Photodynamic Therapy and Pleurectomy With Decortication Surgery<\/h3>\n<p>A recent study from the Raymond and Ruth Perelma School of Medicine at the University of Pennsylvania concluded that the use of photodynamic therapy in conjunction with other treatments exposed a noticeable difference in their patients.<\/p>\n<blockquote><p>\u201cThe results yielded by the radical <a href=\"\/treatment\/surgery\/pleurectomy-decortication\/\">pleurectomy<\/a> and adjuvant (after surgery) PDT were superior to other studies of surgical treatment plans with patients of similar demographics.\u201d<\/p>\n<p><strong>&#8211; Penn Medicine<\/strong><\/p>\n<\/blockquote><style type=\"text\/css\">blockquote{margin:40px 0;padding:0px 15px 0px 60px;position:relative;background-color:#fff}blockquote:before{content:\"\\e99d\";color:#fff;background-color:#0FAEBF;font-size:30px;font-family:\"mesohope\" !important;position:absolute;left:0;top:0;width:50px;height:50px;line-height:50px;text-align:center;border-radius:50%}blockquote p{margin:0}blockquote footer cite{font-size:inherit;line-height:26px;font-style:normal}@media screen and (min-width: 1024px){blockquote{padding:0px 90px 0px 85px}blockquote:before{font-size:35px;width:60px;height:60px;line-height:60px;left:0}}<\/style>\n<p>Doctors found that the preservation of both lungs drastically helped improve the <a href=\"\/mesothelioma\/prognosis\/survival-rate\/\">survival rate<\/a> of their patients, making PDT a key treatment therapy when treating this disease.<\/p>\n<h3>Photodynamic Therapy and Extrapleural Pneumonectomy Surgery<\/h3>\n<p>An initial experimental treatment combined surgery and PDT in 28 patients in two Dutch cancer centers during 1996.<\/p>\n<p>Before <a href=\"\/treatment\/surgery\/extrapleural-pneumonectomy\/\">extrapleural pneumonectomy<\/a> (EPP) surgery (a pleural mesothelioma surgery that removes the lung, portions of the diaphragm, and lining of the lung and heart), the photosensitive solution was given to patients 4 or 6 days before the light would be applied. After that, patients were treated under a subdued light for two weeks.<\/p>\n<p>After the EPP, light probes were strategically placed into transparent tubes to place a seam within the chest cavity. This allowed doctors to remove the highlighted mesothelioma cells, using a combination of light and a photosensitive solution. In this study, 50% of patients were able to localize the disease for an average of 9 months.<\/p>\n<h2 id=\"effects\">Photodynamic Therapy Side Effects<\/h2>\n<p>As with any medical treatment, photodynamic therapy has side effects. However, PDT is still a less invasive option compared to some traditional methods.<\/p>\n<p><strong>Photodynamic therapy side effects may include:<\/strong><\/p>\n<ul class=\"special diamond\">\n<li>Itchiness or burning near the administration area<\/li>\n<li>Light sensitivity<\/li>\n<li>Nausea or vomiting<\/li>\n<li>Shortness of breath<\/li>\n<li>Swollen skin<\/li>\n<\/ul>\n<p>Previously, researchers were concerned about the toxicity levels in patients who underwent PDT. However, with further research and trials, doctors have found ways to limit toxicity levels in patients who undergo PDT.<\/p>\n<p>Patients who undergo photodynamic therapy should avoid exposure to direct sunlight following treatment. The side effects, if any, will last less than 30 days. Ambient, indoor lighting may help break down the photosensitizer, which can speed up recovery time.<\/p>\n<p>The best way to determine whether you&#8217;re a good candidate for photodynamic therapy is to speak with a mesothelioma doctor. Use our <strong>Free Doctor Match<\/strong> to find top specialists in your area.<\/p>\n<div id=\"25223\" class=\"one-off-25223 widget widget_oscar-vque one-off\" data-vqueid=\"25223\"><style type=\"text\/css\" data-style=\"one-off\">.one-off-25223{margin:60px auto}.one-off-25223 a{box-shadow:0 4px 4px 0 rgba(0,0,0,.25);display:block;background:#e4f4f6;padding:20px 25px 200px;text-decoration:none;color:inherit;position:relative;overflow:hidden;max-width:360px;margin:0 auto}.one-off-25223 a::before{background:#0FAEBF;border-radius:50% 50% 0 0;content:'';position:absolute;bottom:0;height:19%;width:135%;left:-60px;z-index:0}.one-off-25223 .vque-content,.one-off-25223 .image-wrap{z-index:1;position:relative}.one-off-25223 .image-wrap{width:100%;position:absolute;left:-10px;bottom:-15px}.one-off-25223 .image-wrap img{position:absolute;bottom:0;width:100%;max-width:unset;left:0}.one-off-25223 .heading{font-size:27px;line-height:33px;text-align:center;display:block;max-width:340px;margin:5px auto 25px}.one-off-25223 ul{list-style:none;margin:-10px auto 22px;text-align:left;font-size:16px;line-height:26px}.one-off-25223 ul li{margin:0 0 15px;position:relative;padding-left:35px}.one-off-25223 ul li::before{font-family:\"mesohope\"!important;speak:none;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;line-height:1;content:\"\\e904\";background:#0FAEBF;width:21px;height:21px;display:block;position:absolute;left:0;top:4px;border-radius:50%;color:#fff;font-size:11px;text-align:center;line-height:21px}.one-off-25223 p{text-align:center}.one-off-25223 .button{padding:12px 16px;display:block}@media screen and (min-width:768px){.one-off-25223 a{max-width:620px;padding:30px 30px 35px;border-radius:0 0 4px 4px}.one-off-25223 a::before{border-radius:50%;height:155%;width:150%;right:-550px;left:unset;bottom:-295px}.one-off-25223 .heading{text-align:left;margin:2px 0 25px;max-width:unset;font-size:24px}.one-off-25223 ul{margin:-7px 0 30px;max-width:365px;line-height:23px}.one-off-25223 ul li::before{top:1px}.one-off-25223 .image-wrap{max-width:unset;position:absolute;right:-25px;bottom:-35px;margin:0 0 -2px;left:unset;width:380px}.one-off-25223 .image-wrap img{position:relative;bottom:0;left:0;width:380px}.one-off-25223 .button{display:inline-block;padding:14px 25px}.one-off-25223 p{text-align:left}}@media screen and (min-width:1150px){.one-off-25223 a{padding:30px}}<\/style><a href=\"\/get-matched\/\" title=\"Get Matched With a Mesothelioma Doctor\" class=\"cte\" data-ce-category=\"In-Content Ads\" data-ce-label=\"Get Matched With a Mesothelioma Doctor Ad\"><div>\r\n    <div class=\"vque-content\">\r\n        <strong class=\"heading\">Get Matched With a Mesothelioma Doctor<\/strong>\r\n        <ul>\r\n            <li>Find top specialists near you<\/li>\r\n            <li>Seek compensation for travel & care<\/li>\r\n            <li>Get medical guidance<\/li>\r\n        <\/ul>\r\n        <p><strong class=\"button arrow\" title=\"Get Matched Now\">Get Matched Now<\/strong><\/p>\r\n    <\/div>\r\n    <div class=\"image-wrap\"><img decoding=\"async\"  src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"\/wp-content\/uploads\/2024\/07\/Doctors-ad.png\" alt=\"Get Matched With a Mesothelioma Doctor\" class=\"lazyload\" ><\/div>\r\n<\/div><\/a><\/div>\n<h2 id=\"treatment\">Undergoing Specialized Mesothelioma Treatment<\/h2>\n<p>Photodynamic therapy is one of many <a href=\"\/treatment\/\">mesothelioma treatments<\/a> that have the potential to change the lives of those living with this cancer. With few side effects and the possibility for a longer survival rate, it is one of the most promising treatments in expanding research for mesothelioma.<\/p>\n<p><a href=\"\/treatment\/photodynamic-therapy\/\">Clinical trials<\/a> are currently accepting patients diagnosed with mesothelioma in experimental photodynamic therapy testing. If you\u2019re interested in participating in photodynamic therapy clinical trials, talk to a specialist or <strong>contact our Patient Advocates at <a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a> today.<\/strong><\/p>\n<div class=\"faq-wrap\"><h2 class=\"faq-wrap-heading\">Mesothelioma Photodynamic Therapy FAQs<\/h2><div class=\"faq\" data-faq=\"1\"><h3 class=\"faq-heading\">Is photodynamic therapy used to treat mesothelioma?<\/h3><div><p><strong>Yes.\u00a0<\/strong>Photodynamic therapy, while still being studied in clinical trials, has been shown to effectively treat mesothelioma and keep cells from spreading to distant parts of the body.<\/p>\n<p>If you&#8217;d like to find a clinical trial using photodynamic therapy, contact our Patient Advocates at <a href=\"tel:+18666088933\" title=\"Click to call (866) 608-8933\" class=\"in-content-tel-link\" data-ce-category=\"Click to Call\" data-ce-label=\"(866) 608-8933\">(866) 608-8933<\/a>.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"2\"><h3 class=\"faq-heading\">Is photodynamic therapy safe?<\/h3><div><p><strong>Yes<\/strong>. Though it&#8217;s still being studied in <a href=\"https:\/\/www.mesotheliomahope.com\/treatment\/clinical-trials\/\">clinical trials<\/a>, photodynamic therapy is actually thought to have fewer side effects than leading treatments like chemotherapy.<\/p>\n<p>In the most extreme cases, patients experience temporary light sensitivity, and the mildest side effect involves itchiness or burning.<\/p>\n<\/div><\/div><div class=\"faq\" data-faq=\"3\"><h3 class=\"faq-heading\">What is the best treatment for mesothelioma?<\/h3><div><p>Each case of mesothelioma is unique. As result, there is not one method of mesothelioma treatment that is the best.<\/p>\n<p>Instead, many mesothelioma specialists may recommend <a href=\"\/treatment\/multimodal-therapy\/\">multimodal therapies<\/a>, which combine multiple treatment methods into one treatment plan.<\/p>\n<\/div><\/div><script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\",\"@type\": \"FAQPage\",\"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Is photodynamic therapy used to treat mesothelioma?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;&lt;strong&gt;Yes.\u00a0&lt;\/strong&gt;Photodynamic therapy, while still being studied in clinical trials, has been shown to effectively treat mesothelioma and keep cells from spreading to distant parts of the body.&lt;\/p&gt;\n&lt;p&gt;If you&amp;#8217;d like to find a clinical trial using photodynamic therapy, contact our Patient Advocates at (866) 608-8933.&lt;\/p&gt;\n\"}},{\"@type\": \"Question\",\"name\": \"Is photodynamic therapy safe?\",\"acceptedAnswer\":{\"@type\": \"Answer\",\"text\": \"&lt;p&gt;&lt;strong&gt;Yes&lt;\/strong&gt;. 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Photodynamic therapy (PDT) is a promising new mesothelioma treatment still undergoing research in clinical trials. As a light-based treatment, photodynamic therapy works by aiming a special light directly at cancer cells treated with light-reactive drugs. This treatment kills mesothelioma cells while causing less damage to surrounding healthy cells. Because mesothelioma is&hellip;<\/p>\n","protected":false},"author":49,"featured_media":0,"parent":39,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-840","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/840","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/comments?post=840"}],"version-history":[{"count":0,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/840\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/pages\/39"}],"wp:attachment":[{"href":"https:\/\/www.mesotheliomahope.com\/wp-json\/wp\/v2\/media?parent=840"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}